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The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity.
Baumgartner CK, Ebrahimi-Nik H, Iracheta-Vellve A, Hamel KM, Olander KE, Davis TGR, McGuire KA, Halvorsen GT, Avila OI, Patel CH, Kim SY, Kammula AV, Muscato AJ, Halliwill K, Geda P, Klinge KL, Xiong Z, Duggan R, Mu L, Yeary MD, Patti JC, Balon TM, Mathew R, Backus C, Kennedy DE, Chen A, Longenecker K, Klahn JT, Hrusch CL, Krishnan N, Hutchins CW, Dunning JP, Bulic M, Tiwari P, Colvin KJ, Chuong CL, Kohnle IC, Rees MG, Boghossian A, Ronan M, Roth JA, Wu MJ, Suermondt JSMT, Knudsen NH, Cheruiyot CK, Sen DR, Griffin GK, Golub TR, El-Bardeesy N, Decker JH, Yang Y, Guffroy M, Fossey S, Trusk P, Sun IM, Liu Y, Qiu W, Sun Q, Paddock MN, Farney EP, Matulenko MA, Beauregard C, Frost JM, Yates KB, Kym PR, Manguso RT. Baumgartner CK, et al. Among authors: patel ch. Nature. 2023 Oct;622(7984):850-862. doi: 10.1038/s41586-023-06575-7. Epub 2023 Oct 4. Nature. 2023. PMID: 37794185 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 36332975
GOT1 regulates CD8+ effector and memory T cell generation.
Xu W, Patel CH, Zhao L, Sun IH, Oh MH, Sun IM, Helms RS, Wen J, Powell JD. Xu W, et al. Among authors: patel ch. Cell Rep. 2023 Jan 31;42(1):111987. doi: 10.1016/j.celrep.2022.111987. Epub 2023 Jan 12. Cell Rep. 2023. PMID: 36640309 Free PMC article.
PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress.
Ranek MJ, Kokkonen-Simon KM, Chen A, Dunkerly-Eyring BL, Vera MP, Oeing CU, Patel CH, Nakamura T, Zhu G, Bedja D, Sasaki M, Holewinski RJ, Van Eyk JE, Powell JD, Lee DI, Kass DA. Ranek MJ, et al. Among authors: patel ch. Nature. 2019 Feb;566(7743):264-269. doi: 10.1038/s41586-019-0895-y. Epub 2019 Jan 30. Nature. 2019. PMID: 30700906 Free PMC article.
Serendipitous Discovery of T Cell-Produced KLK1b22 as a Regulator of Systemic Metabolism.
Arwood ML, Sun IH, Patel CH, Sun IM, Oh MH, Bettencourt IA, Claiborne MD, Chan-Li Y, Zhao L, Waickman AT, Mavrothalassitis O, Wen J, Aja S, Powell JD. Arwood ML, et al. Among authors: patel ch. Immunohorizons. 2023 Jun 1;7(6):493-507. doi: 10.4049/immunohorizons.2300016. Immunohorizons. 2023. PMID: 37358498 Free PMC article.
37 results