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Targeting pancreatic cancer metabolic dependencies through glutamine antagonism.
Encarnación-Rosado J, Sohn ASW, Biancur DE, Lin EY, Osorio-Vasquez V, Rodrick T, González-Baerga D, Zhao E, Yokoyama Y, Simeone DM, Jones DR, Parker SJ, Wild R, Kimmelman AC. Encarnación-Rosado J, et al. Among authors: kimmelman ac. Nat Cancer. 2024 Jan;5(1):85-99. doi: 10.1038/s43018-023-00647-3. Epub 2023 Oct 9. Nat Cancer. 2024. PMID: 37814010 Free PMC article.
Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma.
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, dePinho RA. Zheng H, et al. Among authors: kimmelman ac. Cold Spring Harb Symp Quant Biol. 2008;73:427-37. doi: 10.1101/sqb.2008.73.047. Epub 2009 Jan 15. Cold Spring Harb Symp Quant Biol. 2008. PMID: 19150964
Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production.
Hine C, Kim HJ, Zhu Y, Harputlugil E, Longchamp A, Matos MS, Ramadoss P, Bauerle K, Brace L, Asara JM, Ozaki CK, Cheng SY, Singha S, Ahn KH, Kimmelman A, Fisher FM, Pissios P, Withers DJ, Selman C, Wang R, Yen K, Longo VD, Cohen P, Bartke A, Kopchick JJ, Miller R, Hollenberg AN, Mitchell JR. Hine C, et al. Cell Metab. 2017 Jun 6;25(6):1320-1333.e5. doi: 10.1016/j.cmet.2017.05.003. Cell Metab. 2017. PMID: 28591635 Free PMC article.
Drugging the undruggable RAS: Mission possible?
Cox AD, Fesik SW, Kimmelman AC, Luo J, Der CJ. Cox AD, et al. Among authors: kimmelman ac. Nat Rev Drug Discov. 2014 Nov;13(11):828-51. doi: 10.1038/nrd4389. Epub 2014 Oct 17. Nat Rev Drug Discov. 2014. PMID: 25323927 Free PMC article. Review.
Familial neurogenic tumor syndromes.
Kimmelman A, Liang BC. Kimmelman A, et al. Hematol Oncol Clin North Am. 2001 Dec;15(6):1073-84. doi: 10.1016/s0889-8588(05)70268-9. Hematol Oncol Clin North Am. 2001. PMID: 11770299 Review.
Autophagy in malignant transformation and cancer progression.
Galluzzi L, Pietrocola F, Bravo-San Pedro JM, Amaravadi RK, Baehrecke EH, Cecconi F, Codogno P, Debnath J, Gewirtz DA, Karantza V, Kimmelman A, Kumar S, Levine B, Maiuri MC, Martin SJ, Penninger J, Piacentini M, Rubinsztein DC, Simon HU, Simonsen A, Thorburn AM, Velasco G, Ryan KM, Kroemer G. Galluzzi L, et al. EMBO J. 2015 Apr 1;34(7):856-80. doi: 10.15252/embj.201490784. Epub 2015 Feb 23. EMBO J. 2015. PMID: 25712477 Free PMC article. Review.
115 results