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Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species and strain level diversity and evolution.
Zhang ZJ, Cole CG, Coyne MJ, Lin H, Dylla N, Smith RC, Waligurski E, Ramaswamy R, Woodson C, Burgo V, Little JC, Moran D, Rose A, McMillin M, McSpadden E, Sundararajan A, Sidebottom AM, Pamer EG, Comstock LE. Zhang ZJ, et al. Among authors: waligurski e. bioRxiv [Preprint]. 2024 Mar 9:2024.03.08.584156. doi: 10.1101/2024.03.08.584156. bioRxiv. 2024. PMID: 38496653 Free PMC article. Preprint.
Dietary- and host-derived metabolites are used by diverse gut bacteria for anaerobic respiration.
Little AS, Younker IT, Schechter MS, Bernardino PN, Méheust R, Stemczynski J, Scorza K, Mullowney MW, Sharan D, Waligurski E, Smith R, Ramanswamy R, Leiter W, Moran D, McMillin M, Odenwald MA, Iavarone AT, Sidebottom AM, Sundararajan A, Pamer EG, Eren AM, Light SH. Little AS, et al. Among authors: waligurski e. Nat Microbiol. 2024 Jan;9(1):55-69. doi: 10.1038/s41564-023-01560-2. Epub 2024 Jan 4. Nat Microbiol. 2024. PMID: 38177297
Bifidobacteria metabolize lactulose to optimize gut metabolites and prevent systemic infection in patients with liver disease.
Odenwald MA, Lin H, Lehmann C, Dylla NP, Cole CG, Mostad JD, Pappas TE, Ramaswamy R, Moran A, Hutchison AL, Stutz MR, Dela Cruz M, Adler E, Boissiere J, Khalid M, Cantoral J, Haro F, Oliveira RA, Waligurski E, Cotter TG, Light SH, Beavis KG, Sundararajan A, Sidebottom AM, Reddy KG, Paul S, Pillai A, Te HS, Rinella ME, Charlton MR, Pamer EG, Aronsohn AI. Odenwald MA, et al. Among authors: waligurski e. Nat Microbiol. 2023 Nov;8(11):2033-2049. doi: 10.1038/s41564-023-01493-w. Epub 2023 Oct 16. Nat Microbiol. 2023. PMID: 37845315 Free PMC article.
Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis.
Chatterjee S, Yabaji SM, Rukhlenko OS, Bhattacharya B, Waligurski E, Vallavoju N, Ray S, Kholodenko BN, Brown LE, Beeler AB, Ivanov AR, Kobzik L, Porco JA Jr, Kramnik I. Chatterjee S, et al. Among authors: waligurski e. iScience. 2021 Jul 10;24(8):102845. doi: 10.1016/j.isci.2021.102845. eCollection 2021 Aug 20. iScience. 2021. PMID: 34381970 Free PMC article.
Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria.
Bess EN, Bisanz JE, Yarza F, Bustion A, Rich BE, Li X, Kitamura S, Waligurski E, Ang QY, Alba DL, Spanogiannopoulos P, Nayfach S, Koliwad SK, Wolan DW, Franke AA, Turnbaugh PJ. Bess EN, et al. Among authors: waligurski e. Nat Microbiol. 2020 Jan;5(1):56-66. doi: 10.1038/s41564-019-0596-1. Epub 2019 Nov 4. Nat Microbiol. 2020. PMID: 31686027 Free PMC article.