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Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors.
Yadav MK, Maharana J, Yadav R, Saha S, Sarma P, Soni C, Singh V, Saha S, Ganguly M, Li XX, Mohapatra S, Mishra S, Khant HA, Chami M, Woodruff TM, Banerjee R, Shukla AK, Gati C. Yadav MK, et al. Among authors: sarma p. Cell. 2023 Oct 26;186(22):4956-4973.e21. doi: 10.1016/j.cell.2023.09.020. Epub 2023 Oct 17. Cell. 2023. PMID: 37852260 Free PMC article.
Scratching the itch with cryo-EM.
Maharana J, Sarma P, Shukla AK. Maharana J, et al. Among authors: sarma p. Nat Chem Biol. 2022 Mar;18(3):242-243. doi: 10.1038/s41589-021-00959-4. Nat Chem Biol. 2022. PMID: 35046612 Free PMC article.
Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody.
Baidya M, Chaturvedi M, Dwivedi-Agnihotri H, Ranjan A, Devost D, Namkung Y, Stepniewski TM, Pandey S, Baruah M, Panigrahi B, Sarma P, Yadav MK, Maharana J, Banerjee R, Kawakami K, Inoue A, Selent J, Laporte SA, Hébert TE, Shukla AK. Baidya M, et al. Among authors: sarma p. Nat Commun. 2022 Aug 8;13(1):4634. doi: 10.1038/s41467-022-32386-x. Nat Commun. 2022. PMID: 35941121 Free PMC article.
Structural snapshot of a β-arrestin-biased receptor.
Sarma P, Banerjee R, Shukla AK. Sarma P, et al. Trends Pharmacol Sci. 2023 Jan;44(1):1-3. doi: 10.1016/j.tips.2022.08.005. Epub 2022 Aug 31. Trends Pharmacol Sci. 2023. PMID: 36057461 Free PMC article.
Resonating with the signaling bias of CXCR7.
Sarma P, Shukla AK. Sarma P, et al. Mol Cell. 2022 Sep 15;82(18):3318-3320. doi: 10.1016/j.molcel.2022.08.020. Mol Cell. 2022. PMID: 36113411 Free PMC article.
Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors.
Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK. Maharana J, et al. Among authors: sarma p. Science. 2024 Jan 5;383(6678):101-108. doi: 10.1126/science.adj3347. Epub 2024 Jan 4. Science. 2024. PMID: 38175886 Free PMC article.
992 results