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The bone marrow is the primary site of thrombopoiesis.
Asquith NL, Carminita E, Camacho V, Rodriguez-Romera A, Stegner D, Freire D, Becker IC, Machlus KR, Khan AO, Italiano JE. Asquith NL, et al. Among authors: machlus kr. Blood. 2024 Jan 18;143(3):272-278. doi: 10.1182/blood.2023020895. Blood. 2024. PMID: 37879046
Teamwork makes the dream work in thrombopoiesis.
Asquith NL, Machlus KR. Asquith NL, et al. Among authors: machlus kr. Blood. 2019 Sep 5;134(10):791-792. doi: 10.1182/blood.2019002306. Blood. 2019. PMID: 31488457 Free article. No abstract available.
CCL5 derived from platelets increases megakaryocyte proplatelet formation.
Machlus KR, Johnson KE, Kulenthirarajan R, Forward JA, Tippy MD, Soussou TS, El-Husayni SH, Wu SK, Wang S, Watnick RS, Italiano JE Jr, Battinelli EM. Machlus KR, et al. Blood. 2016 Feb 18;127(7):921-6. doi: 10.1182/blood-2015-05-644583. Epub 2015 Dec 8. Blood. 2016. PMID: 26647394 Free PMC article.
Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies.
Khan AO, Rodriguez-Romera A, Reyat JS, Olijnik AA, Colombo M, Wang G, Wen WX, Sousos N, Murphy LC, Grygielska B, Perrella G, Mahony CB, Ling RE, Elliott NE, Karali CS, Stone AP, Kemble S, Cutler EA, Fielding AK, Croft AP, Bassett D, Poologasundarampillai G, Roy A, Gooding S, Rayes J, Machlus KR, Psaila B. Khan AO, et al. Among authors: machlus kr. Cancer Discov. 2023 Feb 6;13(2):364-385. doi: 10.1158/2159-8290.CD-22-0199. Cancer Discov. 2023. PMID: 36351055 Free PMC article.
Spatial transcriptomics of murine bone marrow megakaryocytes at single-cell resolution.
Tilburg J, Stone AP, Billingsley JM, Scoville DK, Pavenko A, Liang Y, Italiano JE Jr, Machlus KR. Tilburg J, et al. Among authors: machlus kr. Res Pract Thromb Haemost. 2023 Apr 20;7(4):100158. doi: 10.1016/j.rpth.2023.100158. eCollection 2023 May. Res Pract Thromb Haemost. 2023. PMID: 37255850 Free PMC article.
59 results