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APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease.
Jackson RJ, Keiser MS, Meltzer JC, Fykstra DP, Dierksmeier SE, Hajizadeh S, Kreuzer J, Morris R, Melloni A, Nakajima T, Tecedor L, Ranum PT, Carrell E, Chen Y, Nishtar MA, Holtzman DM, Haas W, Davidson BL, Hyman BT. Jackson RJ, et al. Among authors: kreuzer j. Mol Ther. 2024 May 1;32(5):1373-1386. doi: 10.1016/j.ymthe.2024.03.024. Epub 2024 Mar 19. Mol Ther. 2024. PMID: 38504517 Free article.
Genetic retargeting of E3 ligases to enhance CAR T cell therapy.
Lane IC, Kembuan G, Carreiro J, Kann MC, Lin W, Bouffard AA, Kreuzer J, Morris R, Schneider EM, Kim JY, Zou C, Salas-Benito D, Gasser JA, Leick MB, Słabicki M, Haas W, Maus MV, Jan M. Lane IC, et al. Among authors: kreuzer j. Cell Chem Biol. 2024 Feb 15;31(2):338-348.e5. doi: 10.1016/j.chembiol.2023.10.024. Epub 2023 Nov 20. Cell Chem Biol. 2024. PMID: 37989314
Regulation of RNA methylation by therapy treatment, promotes tumor survival.
Bukhari SI, Truesdell SS, Datta C, Choudhury P, Wu KQ, Shrestha J, Maharjan R, Plotsker E, Elased R, Laisa S, Bhambhani V, Lin Y, Kreuzer J, Morris R, Koh SB, Ellisen LW, Haas W, Ly A, Vasudevan S. Bukhari SI, et al. Among authors: kreuzer j. bioRxiv [Preprint]. 2023 May 20:2023.05.19.540602. doi: 10.1101/2023.05.19.540602. bioRxiv. 2023. PMID: 37292633 Free PMC article. Preprint.
SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers.
Shi L, Shen W, Davis MI, Kong K, Vu P, Saha SK, Adil R, Kreuzer J, Egan R, Lee TD, Greninger P, Shrimp JH, Zhao W, Wei TY, Zhou M, Eccleston J, Sussman J, Manocha U, Weerasekara V, Kondo H, Vijay V, Wu MJ, Kearney SE, Ho J, McClanaghan J, Murchie E, Crowther GS, Patnaik S, Boxer MB, Shen M, Ting DT, Kim WY, Stanger BZ, Deshpande V, Ferrone CR, Benes CH, Haas W, Hall MD, Bardeesy N. Shi L, et al. Among authors: kreuzer j. Nat Cancer. 2023 Mar;4(3):365-381. doi: 10.1038/s43018-023-00523-0. Epub 2023 Mar 13. Nat Cancer. 2023. PMID: 36914816 Free PMC article.
Neutrophil profiles of pediatric COVID-19 and multisystem inflammatory syndrome in children.
Boribong BP, LaSalle TJ, Bartsch YC, Ellett F, Loiselle ME, Davis JP, Gonye ALK, Sykes DB, Hajizadeh S, Kreuzer J, Pillai S, Haas W, Edlow AG, Fasano A, Alter G, Irimia D, Sade-Feldman M, Yonker LM. Boribong BP, et al. Among authors: kreuzer j. Cell Rep Med. 2022 Dec 20;3(12):100848. doi: 10.1016/j.xcrm.2022.100848. Epub 2022 Nov 21. Cell Rep Med. 2022. PMID: 36476388 Free PMC article.
Ribosome changes reprogram translation for chemosurvival in G0 leukemic cells.
Datta C, Truesdell SS, Wu KQ, Bukhari SIA, Ngue H, Buchanan B, Le Tonqueze O, Lee S, Kollu S, Granovetter MA, Boukhali M, Kreuzer J, Batool MS, Balaj L, Haas W, Vasudevan S. Datta C, et al. Among authors: kreuzer j. Sci Adv. 2022 Oct 28;8(43):eabo1304. doi: 10.1126/sciadv.abo1304. Epub 2022 Oct 28. Sci Adv. 2022. PMID: 36306353 Free PMC article.
202 results