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A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study.
Jackson HR, Zandstra J, Menikou S, Hamilton MS, McArdle AJ, Fischer R, Thorne AM, Huang H, Tanck MW, Jansen MH, De T, Agyeman PKA, Von Both U, Carrol ED, Emonts M, Eleftheriou I, Van der Flier M, Fink C, Gloerich J, De Groot R, Moll HA, Pokorn M, Pollard AJ, Schlapbach LJ, Tsolia MN, Usuf E, Wright VJ, Yeung S, Zavadska D, Zenz W, Coin LJM, Casals-Pascual C, Cunnington AJ, Martinon-Torres F, Herberg JA, de Jonge MI, Levin M, Kuijpers TW, Kaforou M; PERFORM consortium. Jackson HR, et al. Among authors: kaforou m. Lancet Digit Health. 2023 Nov;5(11):e774-e785. doi: 10.1016/S2589-7500(23)00149-8. Lancet Digit Health. 2023. PMID: 37890901 Free article.
A Novel Combination of Host Protein Biomarkers to Distinguish Bacterial From Viral Infections in Febrile Children in Emergency Care.
Tan CD, van den Broek B, Womersley RS, Kaforou M, Hagedoorn NN, van der Flier M, Jackson H, Moll HA, Snijder R, de Jonge MI, Vermont CL; PERFORM Consortium. Tan CD, et al. Among authors: kaforou m. Pediatr Infect Dis J. 2023 Jul 1;42(7):e235-e242. doi: 10.1097/INF.0000000000003952. Epub 2023 May 17. Pediatr Infect Dis J. 2023. PMID: 37200500
Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study.
Shah P, Voice M, Calvo-Bado L, Rivero-Calle I, Morris S, Nijman R, Broderick C, De T, Eleftheriou I, Galassini R, Khanijau A, Kolberg L, Kolnik M, Rudzate A, Sagmeister MG, Schweintzger NA, Secka F, Thakker C, van der Velden F, Vermont C, Vincek K, Agyeman PKA, Cunnington AJ, De Groot R, Emonts M, Fidler K, Kuijpers TW, Mommert-Tripon M, Brengel-Pesce K, Mallet F, Moll H, Paulus S, Pokorn M, Pollard A, Schlapbach LJ, Shen CF, Tsolia M, Usuf E, van der Flier M, von Both U, Yeung S, Zavadska D, Zenz W, Wright V, Carrol ED, Kaforou M, Martinon-Torres F, Fink C, Levin M, Herberg J; PERFORM consortium. Shah P, et al. Among authors: kaforou m. Lancet Reg Health Eur. 2023 Jul 26;32:100682. doi: 10.1016/j.lanepe.2023.100682. eCollection 2023 Sep. Lancet Reg Health Eur. 2023. PMID: 37554664 Free PMC article.
Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children.
Herberg JA, Kaforou M, Wright VJ, Shailes H, Eleftherohorinou H, Hoggart CJ, Cebey-López M, Carter MJ, Janes VA, Gormley S, Shimizu C, Tremoulet AH, Barendregt AM, Salas A, Kanegaye J, Pollard AJ, Faust SN, Patel S, Kuijpers T, Martinón-Torres F, Burns JC, Coin LJ, Levin M; IRIS Consortium. Herberg JA, et al. Among authors: kaforou m. JAMA. 2016 Aug 23-30;316(8):835-45. doi: 10.1001/jama.2016.11236. JAMA. 2016. PMID: 27552617 Free PMC article.
Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study.
Martinón-Torres F, Salas A, Rivero-Calle I, Cebey-López M, Pardo-Seco J, Herberg JA, Boeddha NP, Klobassa DS, Secka F, Paulus S, de Groot R, Schlapbach LJ, Driessen GJ, Anderson ST, Emonts M, Zenz W, Carrol ED, Van der Flier M, Levin M; EUCLIDS Consortium. Martinón-Torres F, et al. Lancet Child Adolesc Health. 2018 Jun;2(6):404-414. doi: 10.1016/S2352-4642(18)30113-5. Epub 2018 Apr 28. Lancet Child Adolesc Health. 2018. PMID: 30169282 Free article.
Plasma lipid profiles discriminate bacterial from viral infection in febrile children.
Wang X, Nijman R, Camuzeaux S, Sands C, Jackson H, Kaforou M, Emonts M, Herberg JA, Maconochie I, Carrol ED, Paulus SC, Zenz W, Van der Flier M, de Groot R, Martinon-Torres F, Schlapbach LJ, Pollard AJ, Fink C, Kuijpers TT, Anderson S, Lewis MR, Levin M, McClure M; EUCLIDS consortium. Wang X, et al. Among authors: kaforou m. Sci Rep. 2019 Nov 27;9(1):17714. doi: 10.1038/s41598-019-53721-1. Sci Rep. 2019. PMID: 31776453 Free PMC article.
Kawasaki Disease Patient Stratification and Pathway Analysis Based on Host Transcriptomic and Proteomic Profiles.
Jackson H, Menikou S, Hamilton S, McArdle A, Shimizu C, Galassini R, Huang H, Kim J, Tremoulet A, Thorne A, Fischer R, de Jonge MI, Kuijpers T, Wright V, Burns JC, Casals-Pascual C, Herberg J, Levin M, Kaforou M, On Behalf Of The Perform Consortium. Jackson H, et al. Among authors: kaforou m. Int J Mol Sci. 2021 May 26;22(11):5655. doi: 10.3390/ijms22115655. Int J Mol Sci. 2021. PMID: 34073389 Free PMC article.
A Novel Framework for Phenotyping Children With Suspected or Confirmed Infection for Future Biomarker Studies.
Nijman RG, Oostenbrink R, Moll HA, Casals-Pascual C, von Both U, Cunnington A, De T, Eleftheriou I, Emonts M, Fink C, van der Flier M, de Groot R, Kaforou M, Kohlmaier B, Kuijpers TW, Lim E, Maconochie IK, Paulus S, Martinon-Torres F, Pokorn M, Romaine ST, Calle IR, Schlapbach LJ, Smit FJ, Tsolia M, Usuf E, Wright VJ, Yeung S, Zavadska D, Zenz W, Levin M, Herberg JA, Carrol ED; PERFORM consortium (Personalized Risk assessment in febrile children to optimize Real-life Management across the European Union). Nijman RG, et al. Among authors: kaforou m. Front Pediatr. 2021 Jul 28;9:688272. doi: 10.3389/fped.2021.688272. eCollection 2021. Front Pediatr. 2021. PMID: 34395340 Free PMC article.
81 results