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Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation.
Cell Metab. 2023 Dec 5;35(12):2119-2135.e5. doi: 10.1016/j.cmet.2023.10.003. Epub 2023 Oct 31.
Cell Metab. 2023.
PMID: 37913768
Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics.
Zhang AMY, Chu KH, Daly BF, Ruiter T, Dou Y, Yang JCC, de Winter TJJ, Chhuor J, Wang S, Flibotte S, Zhao YB, Hu X, Li H, Rideout EJ, Schaeffer DF, Johnson JD, Kopp JL.
Zhang AMY, et al. Among authors: yang jcc.
Cancer Metab. 2022 Feb 21;10(1):5. doi: 10.1186/s40170-022-00282-z.
Cancer Metab. 2022.
PMID: 35189981
Free PMC article.
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β-Cell Cre Expression and Reduced Ins1 Gene Dosage Protect Mice From Type 1 Diabetes.
Skovsø S, Overby P, Memar-Zadeh J, Lee JTC, Yang JCC, Shanina I, Sidarala V, Levi-D'Ancona E, Zhu J, Soleimanpour SA, Horwitz MS, Johnson JD.
Skovsø S, et al. Among authors: yang jcc.
Endocrinology. 2022 Oct 11;163(11):bqac144. doi: 10.1210/endocr/bqac144.
Endocrinology. 2022.
PMID: 36048448
Free PMC article.
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Implant Texture and Capsular Contracture: A Review of Cellular and Molecular Pathways.
Wells HJ, Yang JCC, Edelstein-Keshet L, Isaac KV.
Wells HJ, et al. Among authors: yang jcc.
Plast Reconstr Surg Glob Open. 2024 May 14;12(5):e5802. doi: 10.1097/GOX.0000000000005802. eCollection 2024 May.
Plast Reconstr Surg Glob Open. 2024.
PMID: 38746946
Free PMC article.
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