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Antagonism of the brain P2X7 ion channel attenuates repeated social defeat induced microglia reactivity, monocyte recruitment and anxiety-like behavior in male mice.
Biltz RG, Swanson SP, Draime N, Davis AC, Yin W, Goodman EJ, Gallagher NR, Bhattacharya A, Sheridan JF, Godbout JP. Biltz RG, et al. Among authors: bhattacharya a. Brain Behav Immun. 2024 Jan;115:356-373. doi: 10.1016/j.bbi.2023.10.011. Epub 2023 Oct 31. Brain Behav Immun. 2024. PMID: 37914101
A novel radioligand for the ATP-gated ion channel P2X7: [3H] JNJ-54232334.
Lord B, Ameriks MK, Wang Q, Fourgeaud L, Vliegen M, Verluyten W, Haspeslagh P, Carruthers NI, Lovenberg TW, Bonaventure P, Letavic MA, Bhattacharya A. Lord B, et al. Among authors: bhattacharya a. Eur J Pharmacol. 2015 Oct 15;765:551-9. doi: 10.1016/j.ejphar.2015.09.026. Epub 2015 Sep 18. Eur J Pharmacol. 2015. PMID: 26386289
Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432.
Lord B, Aluisio L, Shoblock JR, Neff RA, Varlinskaya EI, Ceusters M, Lovenberg TW, Carruthers N, Bonaventure P, Letavic MA, Deak T, Drinkenburg W, Bhattacharya A. Lord B, et al. Among authors: bhattacharya a. J Pharmacol Exp Ther. 2014 Dec;351(3):628-41. doi: 10.1124/jpet.114.218487. Epub 2014 Sep 30. J Pharmacol Exp Ther. 2014. PMID: 25271258
The evolution of P2X7 antagonists with a focus on CNS indications.
Rech JC, Bhattacharya A, Letavic MA, Savall BM. Rech JC, et al. Among authors: bhattacharya a. Bioorg Med Chem Lett. 2016 Aug 15;26(16):3838-45. doi: 10.1016/j.bmcl.2016.06.048. Epub 2016 Jun 30. Bioorg Med Chem Lett. 2016. PMID: 27426304 Review.
The role of P2X7 receptors in a rodent PCP-induced schizophrenia model.
Koványi B, Csölle C, Calovi S, Hanuska A, Kató E, Köles L, Bhattacharya A, Haller J, Sperlágh B. Koványi B, et al. Among authors: bhattacharya a. Sci Rep. 2016 Nov 8;6:36680. doi: 10.1038/srep36680. Sci Rep. 2016. PMID: 27824163 Free PMC article.
Effects of P2X7 receptor antagonists on hypoxia-induced neonatal seizures in mice.
Rodriguez-Alvarez N, Jimenez-Mateos EM, Engel T, Quinlan S, Reschke CR, Conroy RM, Bhattacharya A, Boylan GB, Henshall DC. Rodriguez-Alvarez N, et al. Among authors: bhattacharya a. Neuropharmacology. 2017 Apr;116:351-363. doi: 10.1016/j.neuropharm.2017.01.005. Epub 2017 Jan 10. Neuropharmacology. 2017. PMID: 28082183
2,346 results