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MUC1-C integrates aerobic glycolysis with suppression of oxidative phosphorylation in triple-negative breast cancer stem cells.
Yamashita N, Withers H, Morimoto Y, Bhattacharya A, Haratake N, Daimon T, Fushimi A, Nakashoji A, Thorner AR, Isenhart E, Rosario S, Long MD, Kufe D. Yamashita N, et al. Among authors: long md. iScience. 2023 Oct 11;26(11):108168. doi: 10.1016/j.isci.2023.108168. eCollection 2023 Nov 17. iScience. 2023. PMID: 37915591 Free PMC article.
Dietary folate levels alter the kinetics and molecular mechanism of prostate cancer recurrence in the CWR22 model.
Affronti HC, Long MD, Rosario SR, Gillard BM, Karasik E, Boerlin CS, Pellerite AJ, Foster BA, Attwood K, Pili R, Wilton JH, Campbell MJ, Smiraglia DJ. Affronti HC, et al. Among authors: long md. Oncotarget. 2017 Oct 20;8(61):103758-103774. doi: 10.18632/oncotarget.21911. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262598 Free PMC article.
Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.
Bianchi-Smiraglia A, Bagati A, Fink EE, Affronti HC, Lipchick BC, Moparthy S, Long MD, Rosario SR, Lightman SM, Moparthy K, Wolff DW, Yun DH, Han Z, Polechetti A, Roll MV, Gitlin II, Leonova KI, Rowsam AM, Kandel ES, Gudkov AV, Bergsagel PL, Lee KP, Smiraglia DJ, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: long md. J Clin Invest. 2018 Oct 1;128(10):4682-4696. doi: 10.1172/JCI70712. Epub 2018 Sep 10. J Clin Invest. 2018. PMID: 30198908 Free PMC article.
MUC1-C represses the RASSF1A tumor suppressor in human carcinoma cells.
Rajabi H, Hata T, Li W, Long MD, Hu Q, Liu S, Raina D, Kui L, Yasumizu Y, Hong D, Samur M, Kufe D. Rajabi H, et al. Among authors: long md. Oncogene. 2019 Nov;38(47):7266-7277. doi: 10.1038/s41388-019-0940-1. Epub 2019 Aug 21. Oncogene. 2019. PMID: 31435022 Free PMC article.
MUC1-C Activates the NuRD Complex to Drive Dedifferentiation of Triple-Negative Breast Cancer Cells.
Hata T, Rajabi H, Takahashi H, Yasumizu Y, Li W, Jin C, Long MD, Hu Q, Liu S, Fushimi A, Yamashita N, Kui L, Hong D, Yamamoto M, Miyo M, Hiraki M, Maeda T, Suzuki Y, Samur MK, Kufe D. Hata T, et al. Among authors: long md. Cancer Res. 2019 Nov 15;79(22):5711-5722. doi: 10.1158/0008-5472.CAN-19-1034. Epub 2019 Sep 13. Cancer Res. 2019. PMID: 31519689 Free PMC article.
Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy.
Affronti HC, Rowsam AM, Pellerite AJ, Rosario SR, Long MD, Jacobi JJ, Bianchi-Smiraglia A, Boerlin CS, Gillard BM, Karasik E, Foster BA, Moser M, Wilton JH, Attwood K, Nikiforov MA, Azabdaftari G, Pili R, Phillips JG, Casero RA Jr, Smiraglia DJ. Affronti HC, et al. Among authors: long md. Nat Commun. 2020 Jan 7;11(1):52. doi: 10.1038/s41467-019-13950-4. Nat Commun. 2020. PMID: 31911608 Free PMC article.
MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer.
Yasumizu Y, Rajabi H, Jin C, Hata T, Pitroda S, Long MD, Hagiwara M, Li W, Hu Q, Liu S, Yamashita N, Fushimi A, Kui L, Samur M, Yamamoto M, Zhang Y, Zhang N, Hong D, Maeda T, Kosaka T, Wong KK, Oya M, Kufe D. Yasumizu Y, et al. Among authors: long md. Nat Commun. 2020 Jan 17;11(1):338. doi: 10.1038/s41467-019-14219-6. Nat Commun. 2020. PMID: 31953400 Free PMC article.
295 results