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Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells.
Reincke SM, von Wardenburg N, Homeyer MA, Kornau HC, Spagni G, Li LY, Kreye J, Sánchez-Sendín E, Blumenau S, Stappert D, Radbruch H, Hauser AE, Künkele A, Edes I, Schmitz D, Prüss H. Reincke SM, et al. Among authors: kunkele a. Cell. 2023 Nov 9;186(23):5084-5097.e18. doi: 10.1016/j.cell.2023.10.001. Epub 2023 Nov 1. Cell. 2023. PMID: 37918394
Tumor-Derived Extracellular Vesicles Impair CD171-Specific CD4+ CAR T Cell Efficacy.
Ali S, Toews K, Schwiebert S, Klaus A, Winkler A, Grunewald L, Oevermann L, Deubzer HE, Tüns A, Jensen MC, Henssen AG, Eggert A, Schulte JH, Schwich E, Rebmann V, Schramm A, Künkele A. Ali S, et al. Among authors: kunkele a. Front Immunol. 2020 Mar 31;11:531. doi: 10.3389/fimmu.2020.00531. eCollection 2020. Front Immunol. 2020. PMID: 32296437 Free PMC article.
A Reproducible Bioprinted 3D Tumor Model Serves as a Preselection Tool for CAR T Cell Therapy Optimization.
Grunewald L, Lam T, Andersch L, Klaus A, Schwiebert S, Winkler A, Gauert A, Heeren-Hagemann AI, Astrahantseff K, Klironomos F, Thomas A, Deubzer HE, Henssen AG, Eggert A, Schulte JH, Anders K, Kloke L, Künkele A. Grunewald L, et al. Among authors: kunkele a. Front Immunol. 2021 Jun 29;12:689697. doi: 10.3389/fimmu.2021.689697. eCollection 2021. Front Immunol. 2021. PMID: 34267756 Free PMC article.
Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells.
Kath J, Du W, Pruene A, Braun T, Thommandru B, Turk R, Sturgeon ML, Kurgan GL, Amini L, Stein M, Zittel T, Martini S, Ostendorf L, Wilhelm A, Akyüz L, Rehm A, Höpken UE, Pruß A, Künkele A, Jacobi AM, Volk HD, Schmueck-Henneresse M, Stripecke R, Reinke P, Wagner DL. Kath J, et al. Among authors: kunkele a. Mol Ther Methods Clin Dev. 2022 Apr 12;25:311-330. doi: 10.1016/j.omtm.2022.03.018. eCollection 2022 Jun 9. Mol Ther Methods Clin Dev. 2022. PMID: 35573047 Free PMC article.
GD2-directed bispecific trifunctional antibody outperforms dinutuximab beta in a murine model for aggressive metastasized neuroblastoma.
Zirngibl F, Ivasko SM, Grunewald L, Klaus A, Schwiebert S, Ruf P, Lindhofer H, Astrahantseff K, Andersch L, Schulte JH, Lode HN, Eggert A, Anders K, Hundsdoerfer P, Künkele A. Zirngibl F, et al. Among authors: kunkele a. J Immunother Cancer. 2021 Jul;9(7):e002923. doi: 10.1136/jitc-2021-002923. J Immunother Cancer. 2021. PMID: 34285106 Free PMC article.
60 results