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Single-cell epigenetic, transcriptional, and protein profiling of latent and active HIV-1 reservoir revealed that IKZF3 promotes HIV-1 persistence.
Immunity. 2023 Nov 14;56(11):2584-2601.e7. doi: 10.1016/j.immuni.2023.10.002. Epub 2023 Nov 2.
Immunity. 2023.
PMID: 37922905
Integration site-dependent HIV-1 promoter activity shapes host chromatin conformation.
Collora JA, Ho YC.
Collora JA, et al.
Genome Res. 2023 Jun;33(6):891-906. doi: 10.1101/gr.277698.123. Epub 2023 Jun 9.
Genome Res. 2023.
PMID: 37295842
Free PMC article.
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Inhibition of a Chromatin and Transcription Modulator, SLTM, Increases HIV-1 Reactivation Identified by a CRISPR Inhibition Screen.
Pedersen SF, Collora JA, Kim RN, Yang K, Razmi A, Catalano AA, Yeh YJ, Mounzer K, Tebas P, Montaner LJ, Ho YC.
Pedersen SF, et al. Among authors: collora ja.
J Virol. 2022 Jul 13;96(13):e0057722. doi: 10.1128/jvi.00577-22. Epub 2022 Jun 22.
J Virol. 2022.
PMID: 35730977
Free PMC article.
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Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones.
Collora JA, Liu R, Pinto-Santini D, Ravindra N, Ganoza C, Lama JR, Alfaro R, Chiarella J, Spudich S, Mounzer K, Tebas P, Montaner LJ, van Dijk D, Duerr A, Ho YC.
Collora JA, et al.
Immunity. 2022 Jun 14;55(6):1013-1031.e7. doi: 10.1016/j.immuni.2022.03.004. Epub 2022 Mar 22.
Immunity. 2022.
PMID: 35320704
Free PMC article.
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The loud minority: Transcriptionally active HIV-1-infected cells survive, proliferate, and persist.
Collora JA, Ho YC.
Collora JA, et al.
Cell. 2022 Jan 20;185(2):227-229. doi: 10.1016/j.cell.2021.12.038.
Cell. 2022.
PMID: 35063069
Free PMC article.
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The single-cell landscape of immunological responses of CD4+ T cells in HIV versus severe acute respiratory syndrome coronavirus 2.
Collora JA, Liu R, Albrecht K, Ho YC.
Collora JA, et al.
Curr Opin HIV AIDS. 2021 Jan;16(1):36-47. doi: 10.1097/COH.0000000000000655.
Curr Opin HIV AIDS. 2021.
PMID: 33165008
Free PMC article.
Review.
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Single-cell transcriptional landscapes reveal HIV-1-driven aberrant host gene transcription as a potential therapeutic target.
Liu R, Yeh YJ, Varabyou A, Collora JA, Sherrill-Mix S, Talbot CC Jr, Mehta S, Albrecht K, Hao H, Zhang H, Pollack RA, Beg SA, Calvi RM, Hu J, Durand CM, Ambinder RF, Hoh R, Deeks SG, Chiarella J, Spudich S, Douek DC, Bushman FD, Pertea M, Ho YC.
Liu R, et al. Among authors: collora ja.
Sci Transl Med. 2020 May 13;12(543):eaaz0802. doi: 10.1126/scitranslmed.aaz0802.
Sci Transl Med. 2020.
PMID: 32404504
Free PMC article.
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