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Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression.
Hu T, Shukla SK, Vernucci E, He C, Wang D, King RJ, Jha K, Siddhanta K, Mullen NJ, Attri KS, Murthy D, Chaika NV, Thakur R, Mulder SE, Pacheco CG, Fu X, High RR, Yu F, Lazenby A, Steegborn C, Lan P, Mehla K, Rotili D, Chaudhary S, Valente S, Tafani M, Mai A, Auwerx J, Verdin E, Tuveson D, Singh PK. Hu T, et al. Gastroenterology. 2021 Nov;161(5):1584-1600. doi: 10.1053/j.gastro.2021.06.045. Epub 2021 Jul 8. Gastroenterology. 2021. PMID: 34245764 Free PMC article.
Potent and Specific Activators for Mitochondrial Sirtuins Sirt3 and Sirt5.
Suenkel B, Valente S, Zwergel C, Weiss S, Di Bello E, Fioravanti R, Aventaggiato M, Amorim JA, Garg N, Kumar S, Lombard DB, Hu T, Singh PK, Tafani M, Palmeira CM, Sinclair D, Mai A, Steegborn C. Suenkel B, et al. Among authors: hu t. J Med Chem. 2022 Oct 27;65(20):14015-14031. doi: 10.1021/acs.jmedchem.2c01215. Epub 2022 Oct 13. J Med Chem. 2022. PMID: 36228194 Free PMC article.
Fatty Acid Oxidation Promotes Apoptotic Resistance and Proinflammatory Phenotype of CD4+ Tissue-resident Memory T cells in Crohn's Disease.
Liang G, Huang J, Chen J, Wen X, Li R, Xie H, Zhang Z, Chen Z, Chen Y, Xian Z, He X, Ke J, Lian L, Lan P, Wu X, Hu T. Liang G, et al. Among authors: hu t. Cell Mol Gastroenterol Hepatol. 2024;17(6):939-964. doi: 10.1016/j.jcmgh.2024.02.014. Epub 2024 Feb 28. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38423357 Free PMC article.
6,497 results