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Evaluation of Acebilustat, a Selective Inhibitor of Leukotriene B4 Biosynthesis, for Treatment of Outpatients With Mild-Moderate Coronavirus Disease 2019: A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial.
Levitt JE, Hedlin H, Duong S, Lu D, Lee J, Bunning B, Elkarra N, Pinsky BA, Heffernan E, Springman E, Moss RB, Bonilla HF, Parsonnet J, Zamanian RT, Langguth JJ, Bollyky J, Khosla C, Nicolls MR, Desai M, Rogers AJ. Levitt JE, et al. Among authors: nicolls mr. Clin Infect Dis. 2023 Jul 26;77(2):186-193. doi: 10.1093/cid/ciad187. Clin Infect Dis. 2023. PMID: 36996150 Free PMC article. Clinical Trial.
A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3.
Bhagwani AR, Ali M, Piper B, Liu M, Hudson J, Kelly N, Bogamuwa S, Yang H, Londino JD, Bednash JS, Farkas D, Mallampalli RK, Nicolls MR, Ryan JJ, Thompson AAR, Chan SY, Gomez D, Goncharova EA, Farkas L. Bhagwani AR, et al. Among authors: nicolls mr. iScience. 2023 Jan 5;26(2):105935. doi: 10.1016/j.isci.2023.105935. eCollection 2023 Feb 17. iScience. 2023. PMID: 36685041 Free PMC article.
3D Imaging Reveals Complex Microvascular Remodeling in the Right Ventricle in Pulmonary Hypertension.
Ichimura K, Boehm M, Andruska AM, Zhang F, Schimmel K, Bonham S, Kabiri A, Kheyfets VO, Ichimura S, Reddy S, Mao Y, Zhang T, Wang G, Santana EJ, Tian X, Essafri I, Vinh R, Tian W, Nicolls MR, Yajima S, Shudo Y, MacArthur JW, Woo YJ, Metzger RJ, Spiekerkoetter E. Ichimura K, et al. Among authors: nicolls mr. Circ Res. 2024 May 21. doi: 10.1161/CIRCRESAHA.123.323546. Online ahead of print. Circ Res. 2024. PMID: 38770652
VIEWING PULMONARY HYPERTENSION THROUGH A PEDIATRIC LENS.
Agarwal S, Fineman J, Cornfield DN, Alvira CM, Zamanian RT, Goss K, Yuan K, Bonnet S, Boucherat O, Pullamsetti S, Alcázar MA, Goncharova E, Kudryashova TV, Nicolls MR, de Jesús Pérez V. Agarwal S, et al. Among authors: nicolls mr. Eur Respir J. 2024 Apr 4:2301518. doi: 10.1183/13993003.01518-2023. Online ahead of print. Eur Respir J. 2024. PMID: 38575157 No abstract available.
B-cells in pulmonary arterial hypertension: friend, foe or bystander?
Sanges S, Tian W, Dubucquoi S, Chang JL, Collet A, Launay D, Nicolls MR. Sanges S, et al. Among authors: nicolls mr. Eur Respir J. 2024 Apr 25;63(4):2301949. doi: 10.1183/13993003.01949-2023. Print 2024 Apr. Eur Respir J. 2024. PMID: 38485150 Free PMC article. Review.
Pericytes contribute to pulmonary vascular remodeling via HIF2α signaling.
Kim H, Liu Y, Kim J, Kim Y, Klouda T, Fisch S, Baek SH, Liu T, Dahlberg S, Hu CJ, Tian W, Jiang X, Kosmas K, Christou HA, Korman BD, Vargas SO, Wu JC, Stenmark KR, Perez VJ, Nicolls MR, Raby BA, Yuan K. Kim H, et al. Among authors: nicolls mr. EMBO Rep. 2024 Feb;25(2):616-645. doi: 10.1038/s44319-023-00054-w. Epub 2024 Jan 19. EMBO Rep. 2024. PMID: 38243138 Free PMC article.
148 results