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SARS-CoV-2 antibodies from children exhibit broad neutralization and belong to adult public clonotypes.
Wall SC, Suryadevara N, Kim C, Shiakolas AR, Holt CM, Irbe EB, Wasdin PT, Suresh YP, Binshtein E, Chen EC, Zost SJ, Canfield E, Crowe JE Jr, Thompson-Arildsen MA, Sheward DJ, Carnahan RH, Georgiev IS. Wall SC, et al. Among authors: sheward dj. Cell Rep Med. 2023 Nov 21;4(11):101267. doi: 10.1016/j.xcrm.2023.101267. Epub 2023 Nov 6. Cell Rep Med. 2023. PMID: 37935199 Free PMC article.
SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses.
Mandolesi M, Sheward DJ, Hanke L, Ma J, Pushparaj P, Perez Vidakovics L, Kim C, Àdori M, Lenart K, Loré K, Castro Dopico X, Coquet JM, McInerney GM, Karlsson Hedestam GB, Murrell B. Mandolesi M, et al. Among authors: sheward dj. Cell Rep Med. 2021 Apr 20;2(4):100252. doi: 10.1016/j.xcrm.2021.100252. Epub 2021 Apr 5. Cell Rep Med. 2021. PMID: 33842900 Free PMC article.
SARS-CoV-2 reactive and neutralizing antibodies discovered by single-cell sequencing of plasma cells and mammalian display.
Ehling RA, Weber CR, Mason DM, Friedensohn S, Wagner B, Bieberich F, Kapetanovic E, Vazquez-Lombardi R, Di Roberto RB, Hong KL, Wagner C, Pataia M, Overath MD, Sheward DJ, Murrell B, Yermanos A, Cuny AP, Savic M, Rudolf F, Reddy ST. Ehling RA, et al. Among authors: sheward dj. Cell Rep. 2022 Jan 18;38(3):110242. doi: 10.1016/j.celrep.2021.110242. Epub 2021 Dec 22. Cell Rep. 2022. PMID: 34998467 Free PMC article.
A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo.
Hanke L, Das H, Sheward DJ, Perez Vidakovics L, Urgard E, Moliner-Morro A, Kim C, Karl V, Pankow A, Smith NL, Porebski B, Fernandez-Capetillo O, Sezgin E, Pedersen GK, Coquet JM, Hällberg BM, Murrell B, McInerney GM. Hanke L, et al. Among authors: sheward dj. Nat Commun. 2022 Jan 10;13(1):155. doi: 10.1038/s41467-021-27610-z. Nat Commun. 2022. PMID: 35013189 Free PMC article.
Evasion of neutralising antibodies by omicron sublineage BA.2.75.
Sheward DJ, Kim C, Fischbach J, Muschiol S, Ehling RA, Björkström NK, Karlsson Hedestam GB, Reddy ST, Albert J, Peacock TP, Murrell B. Sheward DJ, et al. Lancet Infect Dis. 2022 Oct;22(10):1421-1422. doi: 10.1016/S1473-3099(22)00524-2. Epub 2022 Sep 1. Lancet Infect Dis. 2022. PMID: 36058228 Free PMC article. No abstract available.
Omicron sublineage BA.2.75.2 exhibits extensive escape from neutralising antibodies.
Sheward DJ, Kim C, Fischbach J, Sato K, Muschiol S, Ehling RA, Björkström NK, Karlsson Hedestam GB, Reddy ST, Albert J, Peacock TP, Murrell B. Sheward DJ, et al. Lancet Infect Dis. 2022 Nov;22(11):1538-1540. doi: 10.1016/S1473-3099(22)00663-6. Epub 2022 Oct 14. Lancet Infect Dis. 2022. PMID: 36244347 Free PMC article. No abstract available.
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