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733 results

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Page 1
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.
Zhang F, Jonsson AH, Nathan A, Millard N, Curtis M, Xiao Q, Gutierrez-Arcelus M, Apruzzese W, Watts GFM, Weisenfeld D, Nayar S, Rangel-Moreno J, Meednu N, Marks KE, Mantel I, Kang JB, Rumker L, Mears J, Slowikowski K, Weinand K, Orange DE, Geraldino-Pardilla L, Deane KD, Tabechian D, Ceponis A, Firestein GS, Maybury M, Sahbudin I, Ben-Artzi A, Mandelin AM 2nd, Nerviani A, Lewis MJ, Rivellese F, Pitzalis C, Hughes LB, Horowitz D, DiCarlo E, Gravallese EM, Boyce BF; Accelerating Medicines Partnership: RA/SLE Network; Moreland LW, Goodman SM, Perlman H, Holers VM, Liao KP, Filer A, Bykerk VP, Wei K, Rao DA, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S. Zhang F, et al. Among authors: lewis mj. Nature. 2023 Nov;623(7987):616-624. doi: 10.1038/s41586-023-06708-y. Epub 2023 Nov 8. Nature. 2023. PMID: 37938773 Free PMC article.
PTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes.
Bottini A, Wu DJ, Ai R, Le Roux M, Bartok B, Bombardieri M, Doody KM, Zhang V, Sacchetti C, Zoccheddu M, Lonic A, Li X, Boyle DL, Hammaker D, Meng TC, Liu L, Corr M, Stanford SM, Lewis M, Wang W, Firestein GS, Khew-Goodall Y, Pitzalis C, Bottini N. Bottini A, et al. Ann Rheum Dis. 2019 May;78(5):600-609. doi: 10.1136/annrheumdis-2018-213799. Epub 2019 Feb 26. Ann Rheum Dis. 2019. PMID: 30808624 Free PMC article.
Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells.
Twohig JP, Cardus Figueras A, Andrews R, Wiede F, Cossins BC, Derrac Soria A, Lewis MJ, Townsend MJ, Millrine D, Li J, Hill DG, Uceda Fernandez J, Liu X, Szomolay B, Pepper CJ, Taylor PR, Pitzalis C, Tiganis T, Williams NM, Jones GW, Jones SA. Twohig JP, et al. Among authors: lewis mj. Nat Immunol. 2019 Apr;20(4):458-470. doi: 10.1038/s41590-019-0350-0. Epub 2019 Mar 19. Nat Immunol. 2019. PMID: 30890796 Free PMC article.
Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes.
Lewis MJ, Barnes MR, Blighe K, Goldmann K, Rana S, Hackney JA, Ramamoorthi N, John CR, Watson DS, Kummerfeld SK, Hands R, Riahi S, Rocher-Ros V, Rivellese F, Humby F, Kelly S, Bombardieri M, Ng N, DiCicco M, van der Heijde D, Landewé R, van der Helm-van Mil A, Cauli A, McInnes IB, Buckley CD, Choy E, Taylor PC, Townsend MJ, Pitzalis C. Lewis MJ, et al. Cell Rep. 2019 Aug 27;28(9):2455-2470.e5. doi: 10.1016/j.celrep.2019.07.091. Cell Rep. 2019. PMID: 31461658 Free PMC article.
Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC).
Lliso-Ribera G, Humby F, Lewis M, Nerviani A, Mauro D, Rivellese F, Kelly S, Hands R, Bene F, Ramamoorthi N, Hackney JA, Cauli A, Choy EH, Filer A, Taylor PC, McInnes I, Townsend MJ, Pitzalis C. Lliso-Ribera G, et al. Among authors: lewis m. Ann Rheum Dis. 2019 Dec;78(12):1642-1652. doi: 10.1136/annrheumdis-2019-215751. Epub 2019 Oct 2. Ann Rheum Dis. 2019. PMID: 31582377 Free PMC article.
B Cell Synovitis and Clinical Phenotypes in Rheumatoid Arthritis: Relationship to Disease Stages and Drug Exposure.
Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C; PEAC-R4RA Investigators. Rivellese F, et al. Among authors: lewis mj. Arthritis Rheumatol. 2020 May;72(5):714-725. doi: 10.1002/art.41184. Epub 2020 Mar 17. Arthritis Rheumatol. 2020. PMID: 31785084 Free PMC article.
M3C: Monte Carlo reference-based consensus clustering.
John CR, Watson D, Russ D, Goldmann K, Ehrenstein M, Pitzalis C, Lewis M, Barnes M. John CR, et al. Sci Rep. 2020 Feb 4;10(1):1816. doi: 10.1038/s41598-020-58766-1. Sci Rep. 2020. PMID: 32020004 Free PMC article.
733 results