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Ferroptosis inhibition by oleic acid mitigates iron-overload-induced injury.
Mann J, Reznik E, Santer M, Fongheiser MA, Smith N, Hirschhorn T, Zandkarimi F, Soni RK, Dafré AL, Miranda-Vizuete A, Farina M, Stockwell BR. Mann J, et al. Among authors: reznik e. Cell Chem Biol. 2024 Feb 15;31(2):249-264.e7. doi: 10.1016/j.chembiol.2023.10.012. Epub 2023 Nov 8. Cell Chem Biol. 2024. PMID: 37944523
FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation.
Gaschler MM, Andia AA, Liu H, Csuka JM, Hurlocker B, Vaiana CA, Heindel DW, Zuckerman DS, Bos PH, Reznik E, Ye LF, Tyurina YY, Lin AJ, Shchepinov MS, Chan AY, Peguero-Pereira E, Fomich MA, Daniels JD, Bekish AV, Shmanai VV, Kagan VE, Mahal LK, Woerpel KA, Stockwell BR. Gaschler MM, et al. Among authors: reznik e. Nat Chem Biol. 2018 May;14(5):507-515. doi: 10.1038/s41589-018-0031-6. Epub 2018 Apr 2. Nat Chem Biol. 2018. PMID: 29610484 Free PMC article.
Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery.
Ye LF, Reznik E, Korn JM, Lin F, Yang G, Malesky K, Gao H, Loo A, Pagliarini R, Mikkelsen T, Lo DC, deCarvalho AC, Stockwell BR. Ye LF, et al. Among authors: reznik e. Oncotarget. 2020 Jan 28;11(4):443-451. doi: 10.18632/oncotarget.27457. eCollection 2020 Jan 28. Oncotarget. 2020. PMID: 32064048 Free PMC article.
Identification of essential sites of lipid peroxidation in ferroptosis.
von Krusenstiern AN, Robson RN, Qian N, Qiu B, Hu F, Reznik E, Smith N, Zandkarimi F, Estes VM, Dupont M, Hirschhorn T, Shchepinov MS, Min W, Woerpel KA, Stockwell BR. von Krusenstiern AN, et al. Among authors: reznik e. Nat Chem Biol. 2023 Jun;19(6):719-730. doi: 10.1038/s41589-022-01249-3. Epub 2023 Feb 6. Nat Chem Biol. 2023. PMID: 36747055 Free PMC article.
Kinases Controlling Stability of the Oncogenic MYCN Protein.
Smith N, Reznik E, Bisikirska B, Polychronidou V, Wang Q, Zask A, Forouhar F, Califano A, Stockwell BR. Smith N, et al. Among authors: reznik e. ACS Med Chem Lett. 2023 Dec 4;14(12):1664-1672. doi: 10.1021/acsmedchemlett.3c00274. eCollection 2023 Dec 14. ACS Med Chem Lett. 2023. PMID: 38116412
160 results