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Page 1
Transcriptomes and metabolism define mouse and human MAIT cell populations.
Chandra S, Ascui G, Riffelmacher T, Chawla A, Ramírez-Suástegui C, Castelan VC, Seumois G, Simon H, Murray MP, Seo GY, Premlal ALR, Schmiedel B, Verstichel G, Li Y, Lin CH, Greenbaum J, Lamberti J, Murthy R, Nigro J, Cheroutre H, Ottensmeier CH, Hedrick SM, Lu LF, Vijayanand P, Kronenberg M. Chandra S, et al. Among authors: verstichel g. Sci Immunol. 2023 Nov 10;8(89):eabn8531. doi: 10.1126/sciimmunol.abn8531. Epub 2023 Nov 10. Sci Immunol. 2023. PMID: 37948512
CD4+-mediated colitis in mice is independent of the GPR183 and GPR18 pathways.
Dicker M, Li Y, Giles DA, Verstichel G, Castelan VC, Ascui-Gac G, Chou TF, Perez-Jeldres T, Cheroutre H, Kronenberg M. Dicker M, et al. Among authors: verstichel g. Front Immunol. 2022 Oct 28;13:1034648. doi: 10.3389/fimmu.2022.1034648. eCollection 2022. Front Immunol. 2022. PMID: 36389671 Free PMC article.
The checkpoint for agonist selection precedes conventional selection in human thymus.
Verstichel G, Vermijlen D, Martens L, Goetgeluk G, Brouwer M, Thiault N, Van Caeneghem Y, De Munter S, Weening K, Bonte S, Leclercq G, Taghon T, Kerre T, Saeys Y, Van Dorpe J, Cheroutre H, Vandekerckhove B. Verstichel G, et al. Sci Immunol. 2017 Feb 24;2(8):eaah4232. doi: 10.1126/sciimmunol.aah4232. Sci Immunol. 2017. PMID: 28783686 Free PMC article.
Notch induces human T-cell receptor γδ+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway.
Van Coppernolle S, Vanhee S, Verstichel G, Snauwaert S, van der Spek A, Velghe I, Sinnesael M, Heemskerk MH, Taghon T, Leclercq G, Plum J, Langerak AW, Kerre T, Vandekerckhove B. Van Coppernolle S, et al. Among authors: verstichel g. Leukemia. 2012 Jan;26(1):127-38. doi: 10.1038/leu.2011.324. Epub 2011 Nov 4. Leukemia. 2012. PMID: 22051534
A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function.
Larange A, Takazawa I, Kakugawa K, Thiault N, Ngoi S, Olive ME, Iwaya H, Seguin L, Vicente-Suarez I, Becart S, Verstichel G, Balancio A, Altman A, Chang JT, Taniuchi I, Lillemeier B, Kronenberg M, Myers SA, Cheroutre H. Larange A, et al. Among authors: verstichel g. Immunity. 2023 Sep 12;56(9):2054-2069.e10. doi: 10.1016/j.immuni.2023.07.017. Epub 2023 Aug 18. Immunity. 2023. PMID: 37597518
Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities.
Van Caeneghem Y, De Munter S, Tieppo P, Goetgeluk G, Weening K, Verstichel G, Bonte S, Taghon T, Leclercq G, Kerre T, Debets R, Vermijlen D, Abken H, Vandekerckhove B. Van Caeneghem Y, et al. Among authors: verstichel g. Oncoimmunology. 2017 Jan 19;6(3):e1283460. doi: 10.1080/2162402X.2017.1283460. eCollection 2017. Oncoimmunology. 2017. PMID: 28405508 Free PMC article.
In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis.
Vanhee S, De Mulder K, Van Caeneghem Y, Verstichel G, Van Roy N, Menten B, Velghe I, Philippé J, De Bleser D, Lambrecht BN, Taghon T, Leclercq G, Kerre T, Vandekerckhove B. Vanhee S, et al. Among authors: verstichel g. Haematologica. 2015 Feb;100(2):157-66. doi: 10.3324/haematol.2014.112144. Epub 2014 Nov 7. Haematologica. 2015. PMID: 25381126 Free PMC article.
In vitro generation of mature, naive antigen-specific CD8(+) T cells with a single T-cell receptor by agonist selection.
Snauwaert S, Verstichel G, Bonte S, Goetgeluk G, Vanhee S, Van Caeneghem Y, De Mulder K, Heirman C, Stauss H, Heemskerk MH, Taghon T, Leclercq G, Plum J, Langerak AW, Thielemans K, Kerre T, Vandekerckhove B. Snauwaert S, et al. Among authors: verstichel g. Leukemia. 2014 Apr;28(4):830-41. doi: 10.1038/leu.2013.285. Epub 2013 Oct 4. Leukemia. 2014. PMID: 24091848
RHAMM/HMMR (CD168) is not an ideal target antigen for immunotherapy of acute myeloid leukemia.
Snauwaert S, Vanhee S, Goetgeluk G, Verstichel G, Van Caeneghem Y, Velghe I, Philippé J, Berneman ZN, Plum J, Taghon T, Leclercq G, Thielemans K, Kerre T, Vandekerckhove B. Snauwaert S, et al. Among authors: verstichel g. Haematologica. 2012 Oct;97(10):1539-47. doi: 10.3324/haematol.2012.065581. Epub 2012 Apr 24. Haematologica. 2012. PMID: 22532518 Free PMC article.