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Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function.
Xu W, Billon C, Li H, Wilderman A, Qi L, Graves A, Rideb JRDC, Zhao Y, Hayes M, Yu K, Losby M, Hampton CS, Adeyemi CM, Hong SJ, Nasiotis E, Fu C, Oh TG, Fan W, Downes M, Welch RD, Evans RM, Milosavljevic A, Walker JK, Jensen BC, Pei L, Burris T, Zhang L. Xu W, et al. Among authors: billon c. Circulation. 2024 Jan 16;149(3):227-250. doi: 10.1161/CIRCULATIONAHA.123.066542. Epub 2023 Nov 14. Circulation. 2024. PMID: 37961903
Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity.
Billon C, Sitaula S, Banerjee S, Welch R, Elgendy B, Hegazy L, Oh TG, Kazantzis M, Chatterjee A, Chrivia J, Hayes ME, Xu W, Hamilton A, Huss JM, Zhang L, Walker JK, Downes M, Evans RM, Burris TP. Billon C, et al. ACS Chem Biol. 2023 Apr 21;18(4):756-771. doi: 10.1021/acschembio.2c00720. Epub 2023 Mar 29. ACS Chem Biol. 2023. PMID: 36988910
Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915.
Hampton CS, Sitaula S, Billon C, Haynes K, Avdagic A, Wanninayake U, Adeyemi CM, Chatterjee A, Griffett K, Banerjee S, Burris SL, Schoepke E, Boehm T, Bess A, de Vera IMS, Burris TP, Walker JK. Hampton CS, et al. Among authors: billon c. Eur J Med Chem. 2023 Oct 5;258:115582. doi: 10.1016/j.ejmech.2023.115582. Epub 2023 Jun 25. Eur J Med Chem. 2023. PMID: 37421886
A Synthetic ERR Agonist Alleviates Metabolic Syndrome.
Billon C, Schoepke E, Avdagic A, Chatterjee A, Butler AA, Elgendy B, Walker JK, Burris TP. Billon C, et al. J Pharmacol Exp Ther. 2024 Jan 17;388(2):232-240. doi: 10.1124/jpet.123.001733. J Pharmacol Exp Ther. 2024. PMID: 37739806
Emerging Role of Nuclear Receptors for the Treatment of NAFLD and NASH.
Welch RD, Billon C, Losby M, Bedia-Diaz G, Fang Y, Avdagic A, Elgendy B, Burris TP, Griffett K. Welch RD, et al. Among authors: billon c. Metabolites. 2022 Mar 11;12(3):238. doi: 10.3390/metabo12030238. Metabolites. 2022. PMID: 35323681 Free PMC article. Review.
70 results