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Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function.
Xu W, Billon C, Li H, Wilderman A, Qi L, Graves A, Rideb JRDC, Zhao Y, Hayes M, Yu K, Losby M, Hampton CS, Adeyemi CM, Hong SJ, Nasiotis E, Fu C, Oh TG, Fan W, Downes M, Welch RD, Evans RM, Milosavljevic A, Walker JK, Jensen BC, Pei L, Burris T, Zhang L. Xu W, et al. Among authors: downes m. Circulation. 2024 Jan 16;149(3):227-250. doi: 10.1161/CIRCULATIONAHA.123.066542. Epub 2023 Nov 14. Circulation. 2024. PMID: 37961903
Unique forms of human and mouse nuclear receptor corepressor SMRT.
Ordentlich P, Downes M, Xie W, Genin A, Spinner NB, Evans RM. Ordentlich P, et al. Among authors: downes m. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2639-44. doi: 10.1073/pnas.96.6.2639. Proc Natl Acad Sci U S A. 1999. PMID: 10077563 Free PMC article.
Identification of a nuclear domain with deacetylase activity.
Downes M, Ordentlich P, Kao HY, Alvarez JG, Evans RM. Downes M, et al. Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10330-5. doi: 10.1073/pnas.97.19.10330. Proc Natl Acad Sci U S A. 2000. PMID: 10984530 Free PMC article.
Corepressors and nuclear hormone receptor function.
Ordentlich P, Downes M, Evans RM. Ordentlich P, et al. Among authors: downes m. Curr Top Microbiol Immunol. 2001;254:101-16. doi: 10.1007/978-3-662-10595-5_5. Curr Top Microbiol Immunol. 2001. PMID: 11190569 Review. No abstract available.
Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites.
Sonoda J, Chong LW, Downes M, Barish GD, Coulter S, Liddle C, Lee CH, Evans RM. Sonoda J, et al. Among authors: downes m. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2198-203. doi: 10.1073/pnas.0409481102. Epub 2005 Jan 25. Proc Natl Acad Sci U S A. 2005. PMID: 15671183 Free PMC article.
497 results