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A preclinical model of TB meningitis to determine drug penetration and activity at the sites of disease.
Lanni F, Antilus Sainte R, Hansen M Jr, Parigi P, Kaya F, LoMauro K, Siow B, Wilkinson RJ, Wasserman S, Podell BK, Gengenbacher M, Dartois V. Lanni F, et al. Among authors: dartois v. Antimicrob Agents Chemother. 2023 Dec 14;67(12):e0067123. doi: 10.1128/aac.00671-23. Epub 2023 Nov 15. Antimicrob Agents Chemother. 2023. PMID: 37966227 Free PMC article.
A sterilizing tuberculosis treatment regimen is associated with faster clearance of bacteria in cavitary lesions in marmosets.
Via LE, England K, Weiner DM, Schimel D, Zimmerman MD, Dayao E, Chen RY, Dodd LE, Richardson M, Robbins KK, Cai Y, Hammoud D, Herscovitch P, Dartois V, Flynn JL, Barry CE 3rd. Via LE, et al. Among authors: dartois v. Antimicrob Agents Chemother. 2015 Jul;59(7):4181-9. doi: 10.1128/AAC.00115-15. Epub 2015 May 4. Antimicrob Agents Chemother. 2015. PMID: 25941223 Free PMC article.
The association between sterilizing activity and drug distribution into tuberculosis lesions.
Prideaux B, Via LE, Zimmerman MD, Eum S, Sarathy J, O'Brien P, Chen C, Kaya F, Weiner DM, Chen PY, Song T, Lee M, Shim TS, Cho JS, Kim W, Cho SN, Olivier KN, Barry CE 3rd, Dartois V. Prideaux B, et al. Among authors: dartois v. Nat Med. 2015 Oct;21(10):1223-7. doi: 10.1038/nm.3937. Epub 2015 Sep 7. Nat Med. 2015. PMID: 26343800 Free PMC article.
Rifabutin Is Active against Mycobacterium abscessus Complex.
Aziz DB, Low JL, Wu ML, Gengenbacher M, Teo JWP, Dartois V, Dick T. Aziz DB, et al. Among authors: dartois v. Antimicrob Agents Chemother. 2017 May 24;61(6):e00155-17. doi: 10.1128/AAC.00155-17. Print 2017 Jun. Antimicrob Agents Chemother. 2017. PMID: 28396540 Free PMC article.
Ethambutol Partitioning in Tuberculous Pulmonary Lesions Explains Its Clinical Efficacy.
Zimmerman M, Lestner J, Prideaux B, O'Brien P, Dias-Freedman I, Chen C, Dietzold J, Daudelin I, Kaya F, Blanc L, Chen PY, Park S, Salgame P, Sarathy J, Dartois V. Zimmerman M, et al. Among authors: dartois v. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00924-17. doi: 10.1128/AAC.00924-17. Print 2017 Sep. Antimicrob Agents Chemother. 2017. PMID: 28696241 Free PMC article.
216 results