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Illuminating protein space with a programmable generative model.
Ingraham JB, Baranov M, Costello Z, Barber KW, Wang W, Ismail A, Frappier V, Lord DM, Ng-Thow-Hing C, Van Vlack ER, Tie S, Xue V, Cowles SC, Leung A, Rodrigues JV, Morales-Perez CL, Ayoub AM, Green R, Puentes K, Oplinger F, Panwar NV, Obermeyer F, Root AR, Beam AL, Poelwijk FJ, Grigoryan G. Ingraham JB, et al. Among authors: barber kw. Nature. 2023 Nov;623(7989):1070-1078. doi: 10.1038/s41586-023-06728-8. Epub 2023 Nov 15. Nature. 2023. PMID: 37968394 Free PMC article.
Metabolic stress promotes stop-codon readthrough and phenotypic heterogeneity.
Zhang H, Lyu Z, Fan Y, Evans CR, Barber KW, Banerjee K, Igoshin OA, Rinehart J, Ling J. Zhang H, et al. Among authors: barber kw. Proc Natl Acad Sci U S A. 2020 Sep 8;117(36):22167-22172. doi: 10.1073/pnas.2013543117. Epub 2020 Aug 24. Proc Natl Acad Sci U S A. 2020. PMID: 32839318 Free PMC article.
Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production.
Gassaway BM, Cardone RL, Padyana AK, Petersen MC, Judd ET, Hayes S, Tong S, Barber KW, Apostolidi M, Abulizi A, Sheetz JB, Kshitiz, Aerni HR, Gross S, Kung C, Samuel VT, Shulman GI, Kibbey RG, Rinehart J. Gassaway BM, et al. Among authors: barber kw. Cell Rep. 2019 Dec 10;29(11):3394-3404.e9. doi: 10.1016/j.celrep.2019.11.009. Cell Rep. 2019. PMID: 31825824 Free PMC article.
PKCε contributes to lipid-induced insulin resistance through cross talk with p70S6K and through previously unknown regulators of insulin signaling.
Gassaway BM, Petersen MC, Surovtseva YV, Barber KW, Sheetz JB, Aerni HR, Merkel JS, Samuel VT, Shulman GI, Rinehart J. Gassaway BM, et al. Among authors: barber kw. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8996-E9005. doi: 10.1073/pnas.1804379115. Epub 2018 Sep 4. Proc Natl Acad Sci U S A. 2018. PMID: 30181290 Free PMC article.
40 results