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Synthesis and Preclinical Evaluation of an 18F-Labeled Synaptic Vesicle Glycoprotein 2A PET Imaging Probe: [18F]SynVesT-2.
Cai Z, Li S, Zhang W, Pracitto R, Wu X, Baum E, Finnema SJ, Holden D, Toyonaga T, Lin SF, Lindemann M, Shirali A, Labaree DC, Ropchan J, Nabulsi N, Carson RE, Huang Y. Cai Z, et al. Among authors: toyonaga t. ACS Chem Neurosci. 2020 Feb 19;11(4):592-603. doi: 10.1021/acschemneuro.9b00618. Epub 2020 Feb 4. ACS Chem Neurosci. 2020. PMID: 31961649
In vivo measurement of widespread synaptic loss in Alzheimer's disease with SV2A PET.
Mecca AP, Chen MK, O'Dell RS, Naganawa M, Toyonaga T, Godek TA, Harris JE, Bartlett HH, Zhao W, Nabulsi NB, Wyk BCV, Varma P, Arnsten AFT, Huang Y, Carson RE, van Dyck CH. Mecca AP, et al. Among authors: toyonaga t. Alzheimers Dement. 2020 Jul;16(7):974-982. doi: 10.1002/alz.12097. Epub 2020 May 13. Alzheimers Dement. 2020. PMID: 32400950 Free PMC article.
Quantification of SV2A Binding in Rodent Brain Using [18F]SynVesT-1 and PET Imaging.
Sadasivam P, Fang XT, Toyonaga T, Lee S, Xu Y, Zheng MQ, Spurrier J, Huang Y, Strittmatter SM, Carson RE, Cai Z. Sadasivam P, et al. Among authors: toyonaga t. Mol Imaging Biol. 2021 Jun;23(3):372-381. doi: 10.1007/s11307-020-01567-9. Epub 2020 Nov 30. Mol Imaging Biol. 2021. PMID: 33258040 Free PMC article.
Association of Aβ deposition and regional synaptic density in early Alzheimer's disease: a PET imaging study with [11C]UCB-J.
O'Dell RS, Mecca AP, Chen MK, Naganawa M, Toyonaga T, Lu Y, Godek TA, Harris JE, Bartlett HH, Banks ER, Kominek VL, Zhao W, Nabulsi NB, Ropchan J, Ye Y, Vander Wyk BC, Huang Y, Arnsten AFT, Carson RE, van Dyck CH. O'Dell RS, et al. Among authors: toyonaga t. Alzheimers Res Ther. 2021 Jan 5;13(1):11. doi: 10.1186/s13195-020-00742-y. Alzheimers Res Ther. 2021. PMID: 33402201 Free PMC article.
Association of entorhinal cortical tau deposition and hippocampal synaptic density in older individuals with normal cognition and early Alzheimer's disease.
Mecca AP, Chen MK, O'Dell RS, Naganawa M, Toyonaga T, Godek TA, Harris JE, Bartlett HH, Zhao W, Banks ER, Ni GS, Rogers K, Gallezot JD, Ropchan J, Emery PR, Nabulsi NB, Vander Wyk BC, Arnsten AFT, Huang Y, Carson RE, van Dyck CH. Mecca AP, et al. Among authors: toyonaga t. Neurobiol Aging. 2022 Mar;111:44-53. doi: 10.1016/j.neurobiolaging.2021.11.004. Epub 2021 Nov 20. Neurobiol Aging. 2022. PMID: 34963063 Free PMC article.
Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [11 C]UCB-J.
Mecca AP, O'Dell RS, Sharp ES, Banks ER, Bartlett HH, Zhao W, Lipior S, Diepenbrock NG, Chen MK, Naganawa M, Toyonaga T, Nabulsi NB, Vander Wyk BC, Arnsten AFT, Huang Y, Carson RE, van Dyck CH. Mecca AP, et al. Among authors: toyonaga t. Alzheimers Dement. 2022 Dec;18(12):2527-2536. doi: 10.1002/alz.12582. Epub 2022 Feb 17. Alzheimers Dement. 2022. PMID: 35174954 Free PMC article.
314 results