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Negative modulation of mitochondrial calcium uniporter complex protects neurons against ferroptosis.
Marmolejo-Garza A, Krabbendam IE, Luu MDA, Brouwer F, Trombetta-Lima M, Unal O, O'Connor SJ, Majerníková N, Elzinga CRS, Mammucari C, Schmidt M, Madesh M, Boddeke E, Dolga AM. Marmolejo-Garza A, et al. Among authors: madesh m. Cell Death Dis. 2023 Nov 25;14(11):772. doi: 10.1038/s41419-023-06290-1. Cell Death Dis. 2023. PMID: 38007529 Free PMC article.
Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy.
Chen SJ, Bao L, Keefer K, Shanmughapriya S, Chen L, Lee J, Wang J, Zhang XQ, Hirschler-Laszkiewicz I, Merali S, Merali C, Imamura Y, Dovat S, Madesh M, Cheung JY, Wang HG, Miller BA. Chen SJ, et al. Among authors: madesh m. Cell Death Dis. 2020 Apr 20;11(4):247. doi: 10.1038/s41419-020-2454-8. Cell Death Dis. 2020. PMID: 32312983 Free PMC article.
MICU1 motifs define mitochondrial calcium uniporter binding and activity.
Hoffman NE, Chandramoorthy HC, Shamugapriya S, Zhang X, Rajan S, Mallilankaraman K, Gandhirajan RK, Vagnozzi RJ, Ferrer LM, Sreekrishnanilayam K, Natarajaseenivasan K, Vallem S, Force T, Choi ET, Cheung JY, Madesh M. Hoffman NE, et al. Among authors: madesh m. Cell Rep. 2013 Dec 26;5(6):1576-1588. doi: 10.1016/j.celrep.2013.11.026. Epub 2013 Dec 12. Cell Rep. 2013. PMID: 24332854 Free PMC article.
MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca2+ Stress.
Nemani N, Carvalho E, Tomar D, Dong Z, Ketschek A, Breves SL, Jaña F, Worth AM, Heffler J, Palaniappan P, Tripathi A, Subbiah R, Riitano MF, Seelam A, Manfred T, Itoh K, Meng S, Sesaki H, Craigen WJ, Rajan S, Shanmughapriya S, Caplan J, Prosser BL, Gill DL, Stathopulos PB, Gallo G, Chan DC, Mishra P, Madesh M. Nemani N, et al. Among authors: madesh m. Cell Rep. 2018 Apr 24;23(4):1005-1019. doi: 10.1016/j.celrep.2018.03.098. Cell Rep. 2018. PMID: 29694881 Free PMC article.
MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics.
Tomar D, Dong Z, Shanmughapriya S, Koch DA, Thomas T, Hoffman NE, Timbalia SA, Goldman SJ, Breves SL, Corbally DP, Nemani N, Fairweather JP, Cutri AR, Zhang X, Song J, Jaña F, Huang J, Barrero C, Rabinowitz JE, Luongo TS, Schumacher SM, Rockman ME, Dietrich A, Merali S, Caplan J, Stathopulos P, Ahima RS, Cheung JY, Houser SR, Koch WJ, Patel V, Gohil VM, Elrod JW, Rajan S, Madesh M. Tomar D, et al. Among authors: madesh m. Cell Rep. 2016 May 24;15(8):1673-85. doi: 10.1016/j.celrep.2016.04.050. Epub 2016 May 12. Cell Rep. 2016. PMID: 27184846 Free PMC article.
Complex I and II are required for normal mitochondrial Ca2+ homeostasis.
Jaña F, Bustos G, Rivas J, Cruz P, Urra F, Basualto-Alarcón C, Sagredo E, Ríos M, Lovy A, Dong Z, Cerda O, Madesh M, Cárdenas C. Jaña F, et al. Among authors: madesh m. Mitochondrion. 2019 Nov;49:73-82. doi: 10.1016/j.mito.2019.07.004. Epub 2019 Jul 13. Mitochondrion. 2019. PMID: 31310854 Free PMC article.
176 results