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Negative modulation of mitochondrial calcium uniporter complex protects neurons against ferroptosis.
Marmolejo-Garza A, Krabbendam IE, Luu MDA, Brouwer F, Trombetta-Lima M, Unal O, O'Connor SJ, Majerníková N, Elzinga CRS, Mammucari C, Schmidt M, Madesh M, Boddeke E, Dolga AM. Marmolejo-Garza A, et al. Among authors: trombetta lima m. Cell Death Dis. 2023 Nov 25;14(11):772. doi: 10.1038/s41419-023-06290-1. Cell Death Dis. 2023. PMID: 38007529 Free PMC article.
Mitochondrial transplantation rescues neuronal cells from ferroptosis.
Chen T, Majerníková N, Marmolejo-Garza A, Trombetta-Lima M, Sabogal-Guáqueta AM, Zhang Y, Ten Kate R, Zuidema M, Mulder PPMFA, den Dunnen W, Gosens R, Verpoorte E, Culmsee C, Eisel ULM, Dolga AM. Chen T, et al. Among authors: trombetta lima m. Free Radic Biol Med. 2023 Nov 1;208:62-72. doi: 10.1016/j.freeradbiomed.2023.07.034. Epub 2023 Aug 1. Free Radic Biol Med. 2023. PMID: 37536459 Free article.
Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction.
Sabogal-Guáqueta AM, Marmolejo-Garza A, Trombetta-Lima M, Oun A, Hunneman J, Chen T, Koistinaho J, Lehtonen S, Kortholt A, Wolters JC, Bakker BM, Eggen BJL, Boddeke E, Dolga A. Sabogal-Guáqueta AM, et al. Among authors: trombetta lima m. Nat Commun. 2023 Oct 13;14(1):6454. doi: 10.1038/s41467-023-42096-7. Nat Commun. 2023. PMID: 37833292 Free PMC article.
Novel SK channel positive modulators prevent ferroptosis and excitotoxicity in neuronal cells.
Zhang Y, Shaabani S, Vowinkel K, Trombetta-Lima M, Sabogal-Guáqueta AM, Chen T, Hoekstra J, Lembeck J, Schmidt M, Decher N, Dömling A, Dolga AM. Zhang Y, et al. Among authors: trombetta lima m. Biomed Pharmacother. 2024 Feb;171:116163. doi: 10.1016/j.biopha.2024.116163. Epub 2024 Jan 18. Biomed Pharmacother. 2024. PMID: 38242037 Free article.
Cellular senescence in brain aging and neurodegeneration.
Melo Dos Santos LS, Trombetta-Lima M, Eggen B, Demaria M. Melo Dos Santos LS, et al. Among authors: trombetta lima m. Ageing Res Rev. 2024 Jan;93:102141. doi: 10.1016/j.arr.2023.102141. Epub 2023 Nov 27. Ageing Res Rev. 2024. PMID: 38030088 Free article. Review.
Mitochondrial dysfunction mediates neuronal cell response to DMMB photodynamic therapy.
de Ávila Narciso Gomes R, Marmolejo-Garza A, Haan FJ, García TM, Chen T, Mauthe M, Moreira Franco Parisotto YE, Murakami MM Jr, Marie SKN, Baptista MS, Dolga AM, Trombetta-Lima M. de Ávila Narciso Gomes R, et al. Among authors: trombetta lima m. Biochim Biophys Acta Mol Cell Res. 2023 Mar;1870(3):119429. doi: 10.1016/j.bbamcr.2022.119429. Epub 2023 Jan 3. Biochim Biophys Acta Mol Cell Res. 2023. PMID: 36608805 Free article.
LRRK2 protects immune cells against erastin-induced ferroptosis.
Oun A, Soliman A, Trombetta-Lima M, Tzepapadaki A, Tsagkari D, Kortholt A, Dolga AM. Oun A, et al. Among authors: trombetta lima m. Neurobiol Dis. 2022 Dec;175:105917. doi: 10.1016/j.nbd.2022.105917. Epub 2022 Nov 3. Neurobiol Dis. 2022. PMID: 36336242 Free article.
30 results