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Molecular and functional correction of a deep intronic splicing mutation in CFTR by CRISPR-Cas9 gene editing.
Walker AJ, Graham C, Greenwood M, Woodall M, Maeshima R, O'Hara-Wright M, Sanz DJ, Guerrini I, Aldossary AM, O'Callaghan C, Baines DL, Harrison PT, Hart SL. Walker AJ, et al. Mol Ther Methods Clin Dev. 2023 Oct 18;31:101140. doi: 10.1016/j.omtm.2023.101140. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 38027060 Free PMC article.
New approaches to genetic therapies for cystic fibrosis.
Christopher Boyd A, Guo S, Huang L, Kerem B, Oren YS, Walker AJ, Hart SL. Christopher Boyd A, et al. Among authors: walker aj. J Cyst Fibros. 2020 Mar;19 Suppl 1:S54-S59. doi: 10.1016/j.jcf.2019.12.012. Epub 2020 Jan 13. J Cyst Fibros. 2020. PMID: 31948871 Free article. Review.
Clinical coding of long COVID in primary care 2020-2023 in a cohort of 19 million adults: an OpenSAFELY analysis.
Henderson AD, Butler-Cole BF, Tazare J, Tomlinson LA, Marks M, Jit M, Briggs A, Lin LY, Carlile O, Bates C, Parry J, Bacon SC, Dillingham I, Dennison WA, Costello RE, Wei Y, Walker AJ, Hulme W, Goldacre B, Mehrkar A, MacKenna B; OpenSAFELY Collaborative; Herrett E, Eggo RM. Henderson AD, et al. Among authors: walker aj. EClinicalMedicine. 2024 May 17;72:102638. doi: 10.1016/j.eclinm.2024.102638. eCollection 2024 Jun. EClinicalMedicine. 2024. PMID: 38800803 Free PMC article.
Validation of Patient-Reported Outcomes in Patients With Nonmetastatic Breast Cancer Receiving Comprehensive Nodal Irradiation in the RadComp Trial.
Hahn EA, Pugh SL, Lu HL, Vela AM, Gillespie EF, Nichols EM, Wright JL, MacDonald SM, Cahlon O, Baas C, Braunstein LZ, Fang LC, Freedman GM, Jimenez RB, Kesslering CM, Mishra MV, Mutter RW, Ohri N, Rosen LR, Urbanic JJ, Jagsi R, Mitchell SA, Bekelman JE, Cella D; RadComp (Radiotherapy Comparative Effectiveness Consortium). Hahn EA, et al. Int J Radiat Oncol Biol Phys. 2024 May 13:S0360-3016(24)00436-X. doi: 10.1016/j.ijrobp.2024.03.020. Online ahead of print. Int J Radiat Oncol Biol Phys. 2024. PMID: 38739047 Free article.
Neuroanatomical distribution of fluorophores within adult RXFP3 Cre-tdTomato/YFP mouse brain.
Eraslan IM, Egberts-Brugman M, Read JL, Voglsanger LM, Samarasinghe RM, Hamilton L, Dhar P, Williams RJ, Walker LC, Ch'ng S, Lawrence AJ, Walker AJ, Dean OM, Gundlach AL, Smith CM. Eraslan IM, et al. Among authors: walker aj. Biochem Pharmacol. 2024 May 5;225:116265. doi: 10.1016/j.bcp.2024.116265. Online ahead of print. Biochem Pharmacol. 2024. PMID: 38714277 Free article.
Impact of long COVID on health-related quality-of-life: an OpenSAFELY population cohort study using patient-reported outcome measures (OpenPROMPT).
Carlile O, Briggs A, Henderson AD, Butler-Cole BFC, Tazare J, Tomlinson LA, Marks M, Jit M, Lin LY, Bates C, Parry J, Bacon SCJ, Dillingham I, Dennison WA, Costello RE, Walker AJ, Hulme W, Goldacre B, Mehrkar A, MacKenna B; OpenSAFELY Collaborative; Herrett E, Eggo RM. Carlile O, et al. Among authors: walker aj. Lancet Reg Health Eur. 2024 Apr 24;40:100908. doi: 10.1016/j.lanepe.2024.100908. eCollection 2024 May. Lancet Reg Health Eur. 2024. PMID: 38689605 Free PMC article.
OpenSAFELY: The impact of COVID-19 on azathioprine, leflunomide and methotrexate monitoring, and factors associated with change in monitoring rate.
Brown AD, Fisher L, Curtis HJ, Wiedemann M, Hulme WJ, Speed V, Hopcroft LEM, Cunningham C, Costello RE, Galloway JB, Russell MD, Bechman K, Kurt Z, Croker R, Wood C, Walker AJ, Schaffer AL, Bacon SCJ, Mehrkar A, Hickman G, Bates C, Cockburn J, Parry J, Hester F, Harper S, Goldacre B; OpenSAFELY Collaborative; MacKenna B. Brown AD, et al. Among authors: walker aj. Br J Clin Pharmacol. 2024 Apr 8. doi: 10.1111/bcp.16062. Online ahead of print. Br J Clin Pharmacol. 2024. PMID: 38589944
The impact of COVID-19 on medication reviews in English primary care. An OpenSAFELY-TPP analysis of 20 million adult electronic health records.
OpenSAFELY Collaborative; Wood C, Speed V, Fisher L, Curtis HJ, Schaffer AL, Walker AJ, Croker R, Brown AD, Cunningham C, Hulme WJ, Andrews CD, Butler-Cole BFC, Evans D, Inglesby P, Dillingham I, Bacon SCJ, Davy S, Ward T, Hickman G, Bridges L, O'Dwyer T, Maude S, Smith RM, Mehrkar A, Bates C, Cockburn J, Parry J, Hester F, Harper S, Goldacre B, MacKenna B. OpenSAFELY Collaborative, et al. Among authors: walker aj. Br J Clin Pharmacol. 2024 Mar 26. doi: 10.1111/bcp.16030. Online ahead of print. Br J Clin Pharmacol. 2024. PMID: 38531661
Impact of vaccination on the association of COVID-19 with cardiovascular diseases: An OpenSAFELY cohort study.
Cezard GI, Denholm RE, Knight R, Wei Y, Teece L, Toms R, Forbes HJ, Walker AJ, Fisher L, Massey J, Hopcroft LEM, Horne EMF, Taylor K, Palmer T, Arab MA, Cuitun Coronado JI, Ip SHY, Davy S, Dillingham I, Bacon S, Mehrkar A, Morton CE, Greaves F, Hyams C, Davey Smith G, Macleod J, Chaturvedi N, Goldacre B, Whiteley WN, Wood AM, Sterne JAC, Walker V; Longitudinal Health and Wellbeing and Data and Connectivity UK COVID-19 National Core Studies, CONVALESCENCE study and the OpenSAFELY collaborative. Cezard GI, et al. Among authors: walker aj. Nat Commun. 2024 Mar 11;15(1):2173. doi: 10.1038/s41467-024-46497-0. Nat Commun. 2024. PMID: 38467603 Free PMC article.
413 results