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Tailor made: the art of therapeutic mRNA design.
Nat Rev Drug Discov. 2024 Jan;23(1):67-83. doi: 10.1038/s41573-023-00827-x. Epub 2023 Nov 29.
Nat Rev Drug Discov. 2024.
PMID: 38030688
Review.
Attenuating ribosome load improves protein output from mRNA by limiting translation-dependent mRNA decay.
Bicknell AA, Reid DW, Licata MC, Jones AK, Cheng YM, Li M, Hsiao CJ, Pepin CS, Metkar M, Levdansky Y, Fritz BR, Andrianova EA, Jain R, Valkov E, Köhrer C, Moore MJ.
Bicknell AA, et al. Among authors: pepin cs.
Cell Rep. 2024 Apr 23;43(4):114098. doi: 10.1016/j.celrep.2024.114098. Epub 2024 Apr 15.
Cell Rep. 2024.
PMID: 38625793
Free article.
Item in Clipboard
mRNA therapy restores euglycemia and prevents liver tumors in murine model of glycogen storage disease.
Cao J, Choi M, Guadagnin E, Soty M, Silva M, Verzieux V, Weisser E, Markel A, Zhuo J, Liang S, Yin L, Frassetto A, Graham AR, Burke K, Ketova T, Mihai C, Zalinger Z, Levy B, Besin G, Wolfrom M, Tran B, Tunkey C, Owen E, Sarkis J, Dousis A, Presnyak V, Pepin C, Zheng W, Ci L, Hard M, Miracco E, Rice L, Nguyen V, Zimmer M, Rajarajacholan U, Finn PF, Mithieux G, Rajas F, Martini PGV, Giangrande PH.
Cao J, et al.
Nat Commun. 2021 May 25;12(1):3090. doi: 10.1038/s41467-021-23318-2.
Nat Commun. 2021.
PMID: 34035281
Free PMC article.
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Risk factors for central-line-associated bloodstream infections: a focus on comorbid conditions.
Pepin CS, Thom KA, Sorkin JD, Leekha S, Masnick M, Preas MA, Pineles L, Harris AD.
Pepin CS, et al.
Infect Control Hosp Epidemiol. 2015 Apr;36(4):479-81. doi: 10.1017/ice.2014.81.
Infect Control Hosp Epidemiol. 2015.
PMID: 25782906
Free PMC article.
Item in Clipboard
Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia.
Takala-Harrison S, Jacob CG, Arze C, Cummings MP, Silva JC, Dondorp AM, Fukuda MM, Hien TT, Mayxay M, Noedl H, Nosten F, Kyaw MP, Nhien NT, Imwong M, Bethell D, Se Y, Lon C, Tyner SD, Saunders DL, Ariey F, Mercereau-Puijalon O, Menard D, Newton PN, Khanthavong M, Hongvanthong B, Starzengruber P, Fuehrer HP, Swoboda P, Khan WA, Phyo AP, Nyunt MM, Nyunt MH, Brown TS, Adams M, Pepin CS, Bailey J, Tan JC, Ferdig MT, Clark TG, Miotto O, MacInnis B, Kwiatkowski DP, White NJ, Ringwald P, Plowe CV.
Takala-Harrison S, et al. Among authors: pepin cs.
J Infect Dis. 2015 Mar 1;211(5):670-9. doi: 10.1093/infdis/jiu491. Epub 2014 Sep 1.
J Infect Dis. 2015.
PMID: 25180241
Free PMC article.
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Illicit drug use among pregnant women enrolled in treatment for cigarette smoking cessation.
Gaalema DE, Higgins ST, Pepin CS, Heil SH, Bernstein IM.
Gaalema DE, et al. Among authors: pepin cs.
Nicotine Tob Res. 2013 May;15(5):987-91. doi: 10.1093/ntr/nts220. Epub 2012 Oct 15.
Nicotine Tob Res. 2013.
PMID: 23072871
Free PMC article.
Clinical Trial.
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