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The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent.
Middelburg J, Ghaffari S, Schoufour TAW, Sluijter M, Schaap G, Göynük B, Sala BM, Al-Tamimi L, Scheeren F, Franken KLMC, Akkermans JJLL, Cabukusta B, Joosten SA, Derksen I, Neefjes J, van der Burg SH, Achour A, Wijdeven RHM, Weidanz J, van Hall T. Middelburg J, et al. Among authors: scheeren f. Cell Rep. 2023 Dec 26;42(12):113516. doi: 10.1016/j.celrep.2023.113516. Epub 2023 Dec 3. Cell Rep. 2023. PMID: 38048225 Free article.
Reassessing human MHC-I genetic diversity in T cell studies.
Slieker RC, Warmerdam DO, Vermeer MH, van Doorn R, Heemskerk MHM, Scheeren FA. Slieker RC, et al. Among authors: scheeren fa. Sci Rep. 2024 Apr 4;14(1):7966. doi: 10.1038/s41598-024-58777-2. Sci Rep. 2024. PMID: 38575727 Free PMC article.
CRISPR/Cas9-based Engineering of Immunoglobulin Loci in Hybridoma Cells.
Gall CLM, Fennemann FL, Van Der Schoot JMS, Scheeren FA, Verdoes M. Gall CLM, et al. Among authors: scheeren fa. Bio Protoc. 2023 Feb 20;13(4):e4613. doi: 10.21769/BioProtoc.4613. eCollection 2023 Feb 20. Bio Protoc. 2023. PMID: 36845533 Free PMC article.
PD-L1 checkpoint blockade promotes regulatory T cell activity that underlies therapy resistance.
van Gulijk M, van Krimpen A, Schetters S, Eterman M, van Elsas M, Mankor J, Klaase L, de Bruijn M, van Nimwegen M, van Tienhoven T, van Ijcken W, Boon L, van der Schoot J, Verdoes M, Scheeren F, van der Burg SH, Lambrecht BN, Stadhouders R, Dammeijer F, Aerts J, van Hall T. van Gulijk M, et al. Among authors: scheeren f. Sci Immunol. 2023 May 19;8(83):eabn6173. doi: 10.1126/sciimmunol.abn6173. Epub 2023 May 19. Sci Immunol. 2023. PMID: 37205768
Identification of HLA-E Binding Mycobacterium tuberculosis-Derived Epitopes through Improved Prediction Models.
Ruibal P, Franken KLMC, van Meijgaarden KE, van Wolfswinkel M, Derksen I, Scheeren FA, Janssen GMC, van Veelen PA, Sarfas C, White AD, Sharpe SA, Palmieri F, Petrone L, Goletti D, Abeel T, Ottenhoff THM, Joosten SA. Ruibal P, et al. Among authors: scheeren fa. J Immunol. 2022 Oct 15;209(8):1555-1565. doi: 10.4049/jimmunol.2200122. Epub 2022 Sep 12. J Immunol. 2022. PMID: 36096642 Free PMC article.
Malaria parasite evades mosquito immunity by glutaminyl cyclase-mediated posttranslational protein modification.
Kolli SK, Molina-Cruz A, Araki T, Geurten FJA, Ramesar J, Chevalley-Maurel S, Kroeze HJ, Bezemer S, de Korne C, Withers R, Raytselis N, El Hebieshy AF, Kim RQ, Child MA, Kakuta S, Hisaeda H, Kobayashi H, Annoura T, Hensbergen PJ, Franke-Fayard BM, Barillas-Mury C, Scheeren FA, Janse CJ. Kolli SK, et al. Among authors: scheeren fa. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2209729119. doi: 10.1073/pnas.2209729119. Epub 2022 Aug 22. Proc Natl Acad Sci U S A. 2022. PMID: 35994647 Free PMC article.
Regulatory T Cell Depletion Using a CRISPR Fc-Optimized CD25 Antibody.
van Elsas MJ, van der Schoot JMS, Bartels A, Steuten K, van Dalen D, Wijfjes Z, Figdor CG, van Hall T, van der Burg SH, Verdoes M, Scheeren FA. van Elsas MJ, et al. Among authors: scheeren fa. Int J Mol Sci. 2022 Aug 5;23(15):8707. doi: 10.3390/ijms23158707. Int J Mol Sci. 2022. PMID: 35955841 Free PMC article.
55 results