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Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia.
Tubío-Santamaría N, Jayavelu AK, Schnoeder TM, Eifert T, Hsu CJ, Perner F, Zhang Q, Wenge DV, Hansen FM, Kirkpatrick JM, Jyotsana N, Lane SW, von Eyss B, Deshpande AJ, Kühn MWM, Schwaller J, Cammann C, Seifert U, Ebstein F, Krüger E, Hochhaus A, Heuser M, Ori A, Mann M, Armstrong SA, Heidel FH. Tubío-Santamaría N, et al. Among authors: schwaller j. Mol Cancer. 2023 Dec 4;22(1):196. doi: 10.1186/s12943-023-01907-7. Mol Cancer. 2023. PMID: 38049829 Free PMC article.
Biomolecular Condensates in Myeloid Leukemia: What Do They Tell Us?
Jevtic Z, Allram M, Grebien F, Schwaller J. Jevtic Z, et al. Among authors: schwaller j. Hemasphere. 2023 Jun 27;7(7):e923. doi: 10.1097/HS9.0000000000000923. eCollection 2023 Jul. Hemasphere. 2023. PMID: 37388925 Free PMC article. Review.
ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion.
Bassani B, Simonetti G, Cancila V, Fiorino A, Ciciarello M, Piva A, Khorasani AM, Chiodoni C, Lecis D, Gulino A, Fonzi E, Botti L, Portararo P, Costanza M, Brambilla M, Colombo G, Schwaller J, Tzankov A, Ponzoni M, Ciceri F, Bolli N, Curti A, Tripodo C, Colombo MP, Sangaletti S. Bassani B, et al. Among authors: schwaller j. Cell Rep. 2024 Feb 27;43(2):113794. doi: 10.1016/j.celrep.2024.113794. Epub 2024 Feb 15. Cell Rep. 2024. PMID: 38363677 Free article.
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia.
Lawson H, Holt-Martyn JP, Dembitz V, Kabayama Y, Wang LM, Bellani A, Atwal S, Saffoon N, Durko J, van de Lagemaat LN, De Pace AL, Tumber A, Corner T, Salah E, Arndt C, Brewitz L, Bowen M, Dubusse L, George D, Allen L, Guitart AV, Fung TK, So CWE, Schwaller J, Gallipoli P, O'Carroll D, Schofield CJ, Kranc KR. Lawson H, et al. Among authors: schwaller j. Nat Cancer. 2024 Apr 18. doi: 10.1038/s43018-024-00761-w. Online ahead of print. Nat Cancer. 2024. PMID: 38637657
Galère des jeunes médecins : « Less is more »?
Schmutz T, Le Terrier C, Schwaller J, Guechi Y, Ribordy V. Schmutz T, et al. Among authors: schwaller j. Rev Med Suisse. 2023 Dec 20;19(855):2420. doi: 10.53738/REVMED.2023.19.855.2420. Rev Med Suisse. 2023. PMID: 38117117 French. No abstract available.
TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression.
Heyes E, Wilhelmson AS, Wenzel A, Manhart G, Eder T, Schuster MB, Rzepa E, Pundhir S, D'Altri T, Frank AK, Gentil C, Woessmann J, Schoof EM, Meggendorfer M, Schwaller J, Haferlach T, Grebien F, Porse BT. Heyes E, et al. Among authors: schwaller j. Nat Commun. 2023 Oct 4;14(1):6185. doi: 10.1038/s41467-023-41927-x. Nat Commun. 2023. PMID: 37794021 Free PMC article.
115 results