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ACOX1-mediated peroxisomal fatty acid oxidation contributes to metabolic reprogramming and survival in chronic lymphocytic leukemia.
Tannoury M, Ayoub M, Dehgane L, Nemazanyy I, Dubois K, Izabelle C, Brousse A, Roos-Weil D, Maloum K, Merle-Béral H, Bauvois B, Saubamea B, Chapiro E, Nguyen-Khac F, Garnier D, Susin SA. Tannoury M, et al. Among authors: merle beral h. Leukemia. 2024 Feb;38(2):302-317. doi: 10.1038/s41375-023-02103-8. Epub 2023 Dec 6. Leukemia. 2024. PMID: 38057495
Gain of the short arm of chromosome 2 (2p) is a frequent recurring chromosome aberration in untreated chronic lymphocytic leukemia (CLL) at advanced stages.
Chapiro E, Leporrier N, Radford-Weiss I, Bastard C, Mossafa H, Leroux D, Tigaud I, De Braekeleer M, Terré C, Brizard F, Callet-Bauchu E, Struski S, Veronese L, Fert-Ferrer S, Taviaux S, Lesty C, Davi F, Merle-Béral H, Bernard OA, Sutton L, Raynaud SD, Nguyen-Khac F. Chapiro E, et al. Leuk Res. 2010 Jan;34(1):63-8. doi: 10.1016/j.leukres.2009.03.042. Epub 2009 Apr 29. Leuk Res. 2010. PMID: 19406473
Gain in the short arm of chromosome 2 (2p+) induces gene overexpression and drug resistance in chronic lymphocytic leukemia: analysis of the central role of XPO1.
Cosson A, Chapiro E, Bougacha N, Lambert J, Herbi L, Cung HA, Algrin C, Keren B, Damm F, Gabillaud C, Brunelle-Navas MN, Davi F, Merle-Béral H, Le Garff-Tavernier M, Roos-Weil D, Choquet S, Uzunov M, Morel V, Leblond V, Maloum K, Lepretre S, Feugier P, Lesty C, Lejeune J, Sutton L, Landesman Y, Susin SA, Nguyen-Khac F. Cosson A, et al. Among authors: merle beral h. Leukemia. 2017 Jul;31(7):1625-1629. doi: 10.1038/leu.2017.100. Epub 2017 Mar 27. Leukemia. 2017. PMID: 28344316 No abstract available.
Targeting chronic lymphocytic leukemia with N-methylated thrombospondin-1-derived peptides overcomes drug resistance.
Pramil E, Herbi Bastian L, Denèfle T, Nemati F, Xiao M, Lardé E, Maloum K, Roos-Weil D, Chapiro E, Le Garff-Tavernier M, Davi F, Decaudin D, Sarfati M, Nguyen-Khac F, Merle-Béral H, Karoyan P, Susin SA. Pramil E, et al. Among authors: merle beral h. Blood Adv. 2019 Oct 22;3(20):2920-2933. doi: 10.1182/bloodadvances.2019000350. Blood Adv. 2019. PMID: 31648314 Free PMC article.
Antibody-dependent cellular cytotoxicity of the optimized anti-CD20 monoclonal antibody ublituximab on chronic lymphocytic leukemia cells with the 17p deletion.
Le Garff-Tavernier M, Herbi L, de Romeuf C, Nguyen-Khac F, Davi F, Grelier A, Boudjoghra M, Maloum K, Choquet S, Urbain R, Vieillard V, Merle-Béral H. Le Garff-Tavernier M, et al. Leukemia. 2014 Jan;28(1):230-3. doi: 10.1038/leu.2013.240. Epub 2013 Aug 20. Leukemia. 2014. PMID: 23958919 No abstract available.
Sex chromosome loss may represent a disease-associated clonal population in chronic lymphocytic leukemia.
Chapiro E, Antony-Debre I, Marchay N, Parizot C, Lesty C, Cung HA, Mathis S, Grelier A, Maloum K, Choquet S, Azgui Z, Uzunov M, Leblond V, Merle-Beral H, Sutton L, Davi F, Nguyen-Khac F. Chapiro E, et al. Genes Chromosomes Cancer. 2014 Mar;53(3):240-7. doi: 10.1002/gcc.22134. Epub 2013 Nov 30. Genes Chromosomes Cancer. 2014. PMID: 24424752 Clinical Trial.
CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCγ1 activation: evidence from mice and humans.
Martinez-Torres AC, Quiney C, Attout T, Boullet H, Herbi L, Vela L, Barbier S, Chateau D, Chapiro E, Nguyen-Khac F, Davi F, Le Garff-Tavernier M, Moumné R, Sarfati M, Karoyan P, Merle-Béral H, Launay P, Susin SA. Martinez-Torres AC, et al. PLoS Med. 2015 Mar 3;12(3):e1001796. doi: 10.1371/journal.pmed.1001796. eCollection 2015 Mar. PLoS Med. 2015. PMID: 25734483 Free PMC article.
195 results