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ACOX1-mediated peroxisomal fatty acid oxidation contributes to metabolic reprogramming and survival in chronic lymphocytic leukemia.
Tannoury M, Ayoub M, Dehgane L, Nemazanyy I, Dubois K, Izabelle C, Brousse A, Roos-Weil D, Maloum K, Merle-Béral H, Bauvois B, Saubamea B, Chapiro E, Nguyen-Khac F, Garnier D, Susin SA. Tannoury M, et al. Among authors: nemazanyy i. Leukemia. 2024 Feb;38(2):302-317. doi: 10.1038/s41375-023-02103-8. Epub 2023 Dec 6. Leukemia. 2024. PMID: 38057495
AIF loss deregulates hematopoiesis and reveals different adaptive metabolic responses in bone marrow cells and thymocytes.
Cabon L, Bertaux A, Brunelle-Navas MN, Nemazanyy I, Scourzic L, Delavallée L, Vela L, Baritaud M, Bouchet S, Lopez C, Quang Van V, Garbin K, Chateau D, Gilard F, Sarfati M, Mercher T, Bernard OA, Susin SA. Cabon L, et al. Among authors: nemazanyy i. Cell Death Differ. 2018 May;25(5):983-1001. doi: 10.1038/s41418-017-0035-x. Epub 2018 Jan 11. Cell Death Differ. 2018. PMID: 29323266 Free PMC article.
PIK3CA gain-of-function mutation in adipose tissue induces metabolic reprogramming with Warburg-like effect and severe endocrine disruption.
Ladraa S, Zerbib L, Bayard C, Fraissenon A, Venot Q, Morin G, Garneau AP, Isnard P, Chapelle C, Hoguin C, Fraitag S, Duong JP, Guibaud L, Besançon A, Kaltenbach S, Villarese P, Asnafi V, Broissand C, Goudin N, Dussiot M, Nemazanyy I, Viel T, Autret G, Cruciani-Guglielmacci C, Denom J, Bruneau J, Tavitian B, Legendre C, Dairou J, Lacorte JM, Levy P, Pende M, Polak M, Canaud G. Ladraa S, et al. Among authors: nemazanyy i. Sci Adv. 2022 Dec 9;8(49):eade7823. doi: 10.1126/sciadv.ade7823. Epub 2022 Dec 9. Sci Adv. 2022. PMID: 36490341 Free PMC article.
Mtfp1 ablation enhances mitochondrial respiration and protects against hepatic steatosis.
Patitucci C, Hernández-Camacho JD, Vimont E, Yde S, Cokelaer T, Chaze T, Giai Gianetto Q, Matondo M, Gazi A, Nemazanyy I, Stroud DA, Hock DH, Donnarumma E, Wai T. Patitucci C, et al. Among authors: nemazanyy i. Nat Commun. 2023 Dec 20;14(1):8474. doi: 10.1038/s41467-023-44143-9. Nat Commun. 2023. PMID: 38123539 Free PMC article.
A homoeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolism.
Tighanimine K, Nabuco Leva Ferreira Freitas JA, Nemazanyy I, Bankolé A, Benarroch-Popivker D, Brodesser S, Doré G, Robinson L, Benit P, Ladraa S, Saada YB, Friguet B, Bertolino P, Bernard D, Canaud G, Rustin P, Gilson E, Bischof O, Fumagalli S, Pende M. Tighanimine K, et al. Among authors: nemazanyy i. Nat Metab. 2024 Feb;6(2):323-342. doi: 10.1038/s42255-023-00972-y. Epub 2024 Feb 19. Nat Metab. 2024. PMID: 38409325 Free PMC article.
Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes.
Gautheron J, Lima L, Akinci B, Zammouri J, Auclair M, Ucar SK, Ozen S, Altay C, Bax BE, Nemazanyy I, Lenoir V, Prip-Buus C, Acquaviva-Bourdain C, Lascols O, Fève B, Vigouroux C, Noel E, Jéru I. Gautheron J, et al. Among authors: nemazanyy i. BMC Med. 2022 Mar 28;20(1):95. doi: 10.1186/s12916-022-02296-2. BMC Med. 2022. PMID: 35341481 Free PMC article.
71 results