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N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting.
Mulroney TE, Pöyry T, Yam-Puc JC, Rust M, Harvey RF, Kalmar L, Horner E, Booth L, Ferreira AP, Stoneley M, Sawarkar R, Mentzer AJ, Lilley KS, Smales CM, von der Haar T, Turtle L, Dunachie S, Klenerman P, Thaventhiran JED, Willis AE. Mulroney TE, et al. Among authors: poyry t. Nature. 2024 Jan;625(7993):189-194. doi: 10.1038/s41586-023-06800-3. Epub 2023 Dec 6. Nature. 2024. PMID: 38057663 Free PMC article.
Hypoxia: Uncharged tRNA to the Rescue!
Mulroney TE, Pöyry T, Willis AE. Mulroney TE, et al. Among authors: poyry t. Curr Biol. 2021 Jan 11;31(1):R25-R27. doi: 10.1016/j.cub.2020.10.067. Curr Biol. 2021. PMID: 33434482 Free article.
Control of translation elongation in health and disease.
Knight JRP, Garland G, Pöyry T, Mead E, Vlahov N, Sfakianos A, Grosso S, De-Lima-Hedayioglu F, Mallucci GR, von der Haar T, Smales CM, Sansom OJ, Willis AE. Knight JRP, et al. Among authors: poyry t. Dis Model Mech. 2020 Mar 26;13(3):dmm043208. doi: 10.1242/dmm.043208. Dis Model Mech. 2020. PMID: 32298235 Free PMC article. Review.
The cell stress response: extreme times call for post-transcriptional measures.
Pizzinga M, Harvey RF, Garland GD, Mordue R, Dezi V, Ramakrishna M, Sfakianos A, Monti M, Mulroney TE, Poyry T, Willis AE. Pizzinga M, et al. Among authors: poyry t. Wiley Interdiscip Rev RNA. 2020 May;11(3):e1578. doi: 10.1002/wrna.1578. Epub 2019 Nov 21. Wiley Interdiscip Rev RNA. 2020. PMID: 31755249 Review.
Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation.
Soukarieh F, Nowicki MW, Bastide A, Pöyry T, Jones C, Dudek K, Patwardhan G, Meullenet F, Oldham NJ, Walkinshaw MD, Willis AE, Fischer PM. Soukarieh F, et al. Among authors: poyry t. Eur J Med Chem. 2016 Nov 29;124:200-217. doi: 10.1016/j.ejmech.2016.08.047. Epub 2016 Aug 24. Eur J Med Chem. 2016. PMID: 27592390 Free PMC article.
A ribosome-related signature in peripheral blood CLL B cells is linked to reduced survival following treatment.
Sbarrato T, Horvilleur E, Pöyry T, Hill K, Chaplin LC, Spriggs RV, Stoneley M, Wilson L, Jayne S, Vulliamy T, Beck D, Dokal I, Dyer MJ, Yeomans AM, Packham G, Bushell M, Wagner SD, Willis AE. Sbarrato T, et al. Among authors: poyry t. Cell Death Dis. 2016 Jun 2;7(6):e2249. doi: 10.1038/cddis.2016.148. Cell Death Dis. 2016. PMID: 27253413 Free PMC article.
Cap-Independent Translation in Hematological Malignancies.
Horvilleur E, Wilson LA, Bastide A, Piñeiro D, Pöyry TA, Willis AE. Horvilleur E, et al. Among authors: poyry ta. Front Oncol. 2015 Dec 21;5:293. doi: 10.3389/fonc.2015.00293. eCollection 2015. Front Oncol. 2015. PMID: 26734574 Free PMC article. Review.
45 results