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N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting.
Mulroney TE, Pöyry T, Yam-Puc JC, Rust M, Harvey RF, Kalmar L, Horner E, Booth L, Ferreira AP, Stoneley M, Sawarkar R, Mentzer AJ, Lilley KS, Smales CM, von der Haar T, Turtle L, Dunachie S, Klenerman P, Thaventhiran JED, Willis AE. Mulroney TE, et al. Among authors: sawarkar r. Nature. 2024 Jan;625(7993):189-194. doi: 10.1038/s41586-023-06800-3. Epub 2023 Dec 6. Nature. 2024. PMID: 38057663 Free PMC article.
HSP70 binds to specific non-coding RNA and regulates human RNA polymerase III.
Leone S, Srivastava A, Herrero-Ruiz A, Hummel B, Tittel L, Campalastri R, Aprile-Garcia F, Tan JH, Rawat P, Andersson P, Willis AE, Sawarkar R. Leone S, et al. Among authors: sawarkar r. Mol Cell. 2024 Feb 15;84(4):687-701.e7. doi: 10.1016/j.molcel.2024.01.001. Epub 2024 Jan 23. Mol Cell. 2024. PMID: 38266641 Free article.
MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALS.
Pérez-Cabello JA, Silvera-Carrasco L, Franco JM, Capilla-González V, Armaos A, Gómez-Lima M, García-García R, Yap XW, Leal-Lasarte M, Lall D, Baloh RH, Martínez S, Miyata Y, Tartaglia GG, Sawarkar R, García-Domínguez M, Pozo D, Roodveldt C. Pérez-Cabello JA, et al. Among authors: sawarkar r. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2302143120. doi: 10.1073/pnas.2302143120. Epub 2023 Jul 3. Proc Natl Acad Sci U S A. 2023. PMID: 37399380 Free PMC article.
39 results