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GluD1 binds GABA and controls inhibitory plasticity.
Piot L, Heroven C, Bossi S, Zamith J, Malinauskas T, Johnson C, Wennagel D, Stroebel D, Charrier C, Aricescu AR, Mony L, Paoletti P. Piot L, et al. Among authors: aricescu ar. Science. 2023 Dec 22;382(6677):1389-1394. doi: 10.1126/science.adf3406. Epub 2023 Dec 7. Science. 2023. PMID: 38060673
Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer.
Laverty D, Desai R, Uchański T, Masiulis S, Stec WJ, Malinauskas T, Zivanov J, Pardon E, Steyaert J, Miller KW, Aricescu AR. Laverty D, et al. Among authors: aricescu ar. Nature. 2019 Jan;565(7740):516-520. doi: 10.1038/s41586-018-0833-4. Epub 2019 Jan 2. Nature. 2019. PMID: 30602789 Free PMC article.
Differential assembly diversifies GABAA receptor structures and signalling.
Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR. Sente A, et al. Among authors: aricescu ar. Nature. 2022 Apr;604(7904):190-194. doi: 10.1038/s41586-022-04517-3. Epub 2022 Mar 30. Nature. 2022. PMID: 35355020 Free PMC article.
GABAA receptor signalling mechanisms revealed by structural pharmacology.
Masiulis S, Desai R, Uchański T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Zivanov J, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR. Masiulis S, et al. Among authors: aricescu ar. Nature. 2019 Jan;565(7740):454-459. doi: 10.1038/s41586-018-0832-5. Epub 2019 Jan 2. Nature. 2019. PMID: 30602790 Free PMC article.
Structural basis for integration of GluD receptors within synaptic organizer complexes.
Elegheert J, Kakegawa W, Clay JE, Shanks NF, Behiels E, Matsuda K, Kohda K, Miura E, Rossmann M, Mitakidis N, Motohashi J, Chang VT, Siebold C, Greger IH, Nakagawa T, Yuzaki M, Aricescu AR. Elegheert J, et al. Among authors: aricescu ar. Science. 2016 Jul 15;353(6296):295-9. doi: 10.1126/science.aae0104. Science. 2016. PMID: 27418511 Free PMC article.
The molecular basis of drug selectivity for α5 subunit-containing GABAA receptors.
Kasaragod VB, Malinauskas T, Wahid AA, Lengyel J, Knoflach F, Hardwick SW, Jones CF, Chen WN, Lucas X, El Omari K, Chirgadze DY, Aricescu AR, Cecere G, Hernandez MC, Miller PS. Kasaragod VB, et al. Among authors: aricescu ar. Nat Struct Mol Biol. 2023 Dec;30(12):1936-1946. doi: 10.1038/s41594-023-01133-1. Epub 2023 Oct 30. Nat Struct Mol Biol. 2023. PMID: 37903907 Free PMC article.
76 results