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Evaluating the safety, tolerability, and immunogenicity of a 24-valent pneumococcal conjugate vaccine (VAX-24) in healthy adults aged 18 to 64 years: a phase 1/2, double-masked, dose-finding, active-controlled, randomised clinical trial.
Wassil J, Sisti M, Fairman J, Davis M, Fierro C, Bennett S, Johnson D, Migone TS, Nguyen K, Sauer P, Currie M, Iki S, Simon JK. Wassil J, et al. Among authors: fairman j. Lancet Infect Dis. 2024 Mar;24(3):308-318. doi: 10.1016/S1473-3099(23)00572-8. Epub 2023 Dec 4. Lancet Infect Dis. 2024. PMID: 38061367 Clinical Trial.
Non-clinical immunological comparison of a Next-Generation 24-valent pneumococcal conjugate vaccine (VAX-24) using site-specific carrier protein conjugation to the current standard of care (PCV13 and PPV23).
Fairman J, Agarwal P, Barbanel S, Behrens C, Berges A, Burky J, Davey P, Fernsten P, Grainger C, Guo S, Iki S, Iverson M, Kane M, Kapoor N, Marcq O, Migone TS, Sauer P, Wassil J. Fairman J, et al. Vaccine. 2021 May 27;39(23):3197-3206. doi: 10.1016/j.vaccine.2021.03.070. Epub 2021 May 6. Vaccine. 2021. PMID: 33965258 Free article.
Addition of Lauryldimethylamine N-Oxide (LDAO) to a Copper-Free Click Chemistry Reaction Improves the Conjugation Efficiency of a Cell-Free Generated CRM197 Variant to Clinically Important Streptococcus pneumoniae Serotypes.
Bautista L, Pill-Pepe L, Kapoor N, Snyder S, Chu E, Agarwal P, Sardar M, Arulkumar S, Berges A, Iverson M, Behrens C, Marcq O, Fairman J. Bautista L, et al. Among authors: fairman j. ACS Omega. 2022 Sep 20;7(39):34921-34928. doi: 10.1021/acsomega.2c03481. eCollection 2022 Oct 4. ACS Omega. 2022. PMID: 36211053 Free PMC article.
The Group A Streptococcal Vaccine Candidate VAX-A1 Protects against Group B Streptococcus Infection via Cross-Reactive IgG Targeting Virulence Factor C5a Peptidase.
McCabe S, Bjånes E, Hendriks A, Wang Z, van Sorge NM, Pill-Pepe L, Bautista L, Chu E, Codée JDC, Fairman J, Kapoor N, Uchiyama S, Nizet V. McCabe S, et al. Among authors: fairman j. Vaccines (Basel). 2023 Dec 3;11(12):1811. doi: 10.3390/vaccines11121811. Vaccines (Basel). 2023. PMID: 38140215 Free PMC article.
Non-Native Amino Acid Click Chemistry-Based Technology for Site-Specific Polysaccharide Conjugation to a Bacterial Protein Serving as Both Carrier and Vaccine Antigen.
Kapoor N, Uchiyama S, Pill L, Bautista L, Sedra A, Yin L, Regan M, Chu E, Rabara T, Wong M, Davey P, Fairman J, Nizet V. Kapoor N, et al. Among authors: fairman j. ACS Omega. 2022 Jul 11;7(28):24111-24120. doi: 10.1021/acsomega.1c07360. eCollection 2022 Jul 19. ACS Omega. 2022. PMID: 35874267 Free PMC article.
149 results