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Obesity worsens mitochondrial quality control and does not protect against skeletal muscle wasting in murine cancer cachexia.
Cardaci TD, VanderVeen BN, Bullard BM, McDonald SJ, Unger CA, Enos RT, Fan D, Velázquez KT, Frizzell N, Spangenburg EE, Murphy EA. Cardaci TD, et al. Among authors: frizzell n. J Cachexia Sarcopenia Muscle. 2024 Feb;15(1):124-137. doi: 10.1002/jcsm.13391. Epub 2023 Dec 7. J Cachexia Sarcopenia Muscle. 2024. PMID: 38062911 Free PMC article.
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production.
Hooftman A, Peace CG, Ryan DG, Day EA, Yang M, McGettrick AF, Yin M, Montano EN, Huo L, Toller-Kawahisa JE, Zecchini V, Ryan TAJ, Bolado-Carrancio A, Casey AM, Prag HA, Costa ASH, De Los Santos G, Ishimori M, Wallace DJ, Venuturupalli S, Nikitopoulou E, Frizzell N, Johansson C, Von Kriegsheim A, Murphy MP, Jefferies C, Frezza C, O'Neill LAJ. Hooftman A, et al. Among authors: frizzell n. Nature. 2023 Mar;615(7952):490-498. doi: 10.1038/s41586-023-05720-6. Epub 2023 Mar 8. Nature. 2023. PMID: 36890227 Free PMC article.
Depletion of COPI in cancer cells: the role of reactive oxygen species in the induction of lipid accumulation, noncanonical lipophagy and apoptosis.
Gasparian A, Aksenova M, Oliver D, Levina E, Doran R, Lucius M, Piroli G, Oleinik N, Ogretmen B, Mythreye K, Frizzell N, Broude E, Wyatt MD, Shtutman M. Gasparian A, et al. Among authors: frizzell n. Mol Biol Cell. 2022 Dec 1;33(14):ar135. doi: 10.1091/mbc.E21-08-0420. Epub 2022 Oct 12. Mol Biol Cell. 2022. PMID: 36222847 Free PMC article.
Results and Lessons Learned when Implementing Virtual Health Resource Centers to Increase Virtual Care Adoption During the COVID-19 Pandemic.
Armstrong CM, Wilck NR, Murphy J, Herout J, Cone WJ, Johnson AK, Zipper K, Britz B, Betancourt-Flores G, LaFleur M, Vetter B, Dameron B, Frizzell N. Armstrong CM, et al. Among authors: frizzell n. J Technol Behav Sci. 2022;7(1):81-99. doi: 10.1007/s41347-021-00227-1. Epub 2021 Oct 25. J Technol Behav Sci. 2022. PMID: 34722860 Free PMC article.
A chemoproteomic portrait of the oncometabolite fumarate.
Kulkarni RA, Bak DW, Wei D, Bergholtz SE, Briney CA, Shrimp JH, Alpsoy A, Thorpe AL, Bavari AE, Crooks DR, Levy M, Florens L, Washburn MP, Frizzell N, Dykhuizen EC, Weerapana E, Linehan WM, Meier JL. Kulkarni RA, et al. Among authors: frizzell n. Nat Chem Biol. 2019 Apr;15(4):391-400. doi: 10.1038/s41589-018-0217-y. Epub 2019 Feb 4. Nat Chem Biol. 2019. PMID: 30718813 Free PMC article.
Identification of Novel Protein Targets of Dimethyl Fumarate Modification in Neurons and Astrocytes Reveals Actions Independent of Nrf2 Stabilization.
Piroli GG, Manuel AM, Patel T, Walla MD, Shi L, Lanci SA, Wang J, Galloway A, Ortinski PI, Smith DS, Frizzell N. Piroli GG, et al. Among authors: frizzell n. Mol Cell Proteomics. 2019 Mar;18(3):504-519. doi: 10.1074/mcp.RA118.000922. Epub 2018 Dec 26. Mol Cell Proteomics. 2019. PMID: 30587509 Free PMC article.
56 results