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Cotadutide promotes glycogenolysis in people with overweight or obesity diagnosed with type 2 diabetes.
Parker VER, Robertson D, Erazo-Tapia E, Havekes B, Phielix E, de Ligt M, Roumans KHM, Mevenkamp J, Sjoberg F, Schrauwen-Hinderling VB, Johansson E, Chang YT, Esterline R, Smith K, Wilkinson DJ, Hansen L, Johansson L, Ambery P, Jermutus L, Schrauwen P. Parker VER, et al. Among authors: schrauwen p. Nat Metab. 2023 Dec;5(12):2086-2093. doi: 10.1038/s42255-023-00938-0. Epub 2023 Dec 8. Nat Metab. 2023. PMID: 38066113 Free PMC article. Clinical Trial.
Intramyocellular lipid content in human skeletal muscle.
Schrauwen-Hinderling VB, Hesselink MK, Schrauwen P, Kooi ME. Schrauwen-Hinderling VB, et al. Among authors: schrauwen p. Obesity (Silver Spring). 2006 Mar;14(3):357-67. doi: 10.1038/oby.2006.47. Obesity (Silver Spring). 2006. PMID: 16648604 Free article. Review.
Impaired in vivo mitochondrial function but similar intramyocellular lipid content in patients with type 2 diabetes mellitus and BMI-matched control subjects.
Schrauwen-Hinderling VB, Kooi ME, Hesselink MK, Jeneson JA, Backes WH, van Echteld CJ, van Engelshoven JM, Mensink M, Schrauwen P. Schrauwen-Hinderling VB, et al. Among authors: schrauwen p. Diabetologia. 2007 Jan;50(1):113-20. doi: 10.1007/s00125-006-0475-1. Epub 2006 Nov 9. Diabetologia. 2007. PMID: 17093944
Muscular mitochondrial dysfunction and type 2 diabetes mellitus.
Schrauwen-Hinderling VB, Roden M, Kooi ME, Hesselink MK, Schrauwen P. Schrauwen-Hinderling VB, et al. Among authors: schrauwen p. Curr Opin Clin Nutr Metab Care. 2007 Nov;10(6):698-703. doi: 10.1097/MCO.0b013e3282f0eca9. Curr Opin Clin Nutr Metab Care. 2007. PMID: 18089950 Review.
Lower intrinsic ADP-stimulated mitochondrial respiration underlies in vivo mitochondrial dysfunction in muscle of male type 2 diabetic patients.
Phielix E, Schrauwen-Hinderling VB, Mensink M, Lenaers E, Meex R, Hoeks J, Kooi ME, Moonen-Kornips E, Sels JP, Hesselink MK, Schrauwen P. Phielix E, et al. Among authors: schrauwen hinderling vb, schrauwen p. Diabetes. 2008 Nov;57(11):2943-9. doi: 10.2337/db08-0391. Epub 2008 Aug 4. Diabetes. 2008. PMID: 18678616 Free PMC article.
Mitochondrial dysfunction and lipotoxicity.
Schrauwen P, Schrauwen-Hinderling V, Hoeks J, Hesselink MK. Schrauwen P, et al. Among authors: schrauwen hinderling v. Biochim Biophys Acta. 2010 Mar;1801(3):266-71. doi: 10.1016/j.bbalip.2009.09.011. Epub 2009 Sep 24. Biochim Biophys Acta. 2010. PMID: 19782153 Review.
Restoration of muscle mitochondrial function and metabolic flexibility in type 2 diabetes by exercise training is paralleled by increased myocellular fat storage and improved insulin sensitivity.
Meex RC, Schrauwen-Hinderling VB, Moonen-Kornips E, Schaart G, Mensink M, Phielix E, van de Weijer T, Sels JP, Schrauwen P, Hesselink MK. Meex RC, et al. Among authors: schrauwen hinderling vb, schrauwen p. Diabetes. 2010 Mar;59(3):572-9. doi: 10.2337/db09-1322. Epub 2009 Dec 22. Diabetes. 2010. PMID: 20028948 Free PMC article. Clinical Trial.
324 results