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213 results

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Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): protocol for a multicentre phase 3 pragmatic clinical and cost-effectiveness randomised trial in the UK.
Walsh TS, Aitken LM, McKenzie CA, Boyd J, Macdonald A, Giddings A, Hope D, Norrie J, Weir C, Parker RA, Lone NI, Emerson L, Kydonaki K, Creagh-Brown B, Morris S, McAuley DF, Dark P, Wise MP, Gordon AC, Perkins G, Reade M, Blackwood B, MacLullich A, Glen R, Page VJ. Walsh TS, et al. Among authors: reade m. BMJ Open. 2023 Dec 10;13(12):e078645. doi: 10.1136/bmjopen-2023-078645. BMJ Open. 2023. PMID: 38072483 Free PMC article.
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Shehabi Y, Howe BD, Bellomo R, Arabi YM, Bailey M, Bass FE, Bin Kadiman S, McArthur CJ, Murray L, Reade MC, Seppelt IM, Takala J, Wise MP, Webb SA; ANZICS Clinical Trials Group and the SPICE III Investigators. Shehabi Y, et al. Among authors: reade mc. N Engl J Med. 2019 Jun 27;380(26):2506-2517. doi: 10.1056/NEJMoa1904710. Epub 2019 May 19. N Engl J Med. 2019. PMID: 31112380 Clinical Trial.
Early sedation with dexmedetomidine in ventilated critically ill patients and heterogeneity of treatment effect in the SPICE III randomised controlled trial.
Shehabi Y, Serpa Neto A, Howe BD, Bellomo R, Arabi YM, Bailey M, Bass FE, Kadiman SB, McArthur CJ, Reade MC, Seppelt IM, Takala J, Wise MP, Webb SA; SPICE III Study Investigators. Shehabi Y, et al. Among authors: reade mc. Intensive Care Med. 2021 Apr;47(4):455-466. doi: 10.1007/s00134-021-06356-8. Epub 2021 Mar 8. Intensive Care Med. 2021. PMID: 33686482 Free PMC article. Clinical Trial.
Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose-associated 90-Day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE III).
Shehabi Y, Serpa Neto A, Bellomo R, Howe BD, Arabi YM, Bailey M, Bass FE, Bin Kadiman S, McArthur CJ, Reade MC, Seppelt IM, Takala J, Wise MP, Webb SA; SPICE III Study Investigators. Shehabi Y, et al. Among authors: reade mc. Am J Respir Crit Care Med. 2023 Apr 1;207(7):876-886. doi: 10.1164/rccm.202206-1208OC. Am J Respir Crit Care Med. 2023. PMID: 36215171 Clinical Trial.
Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B trial): protocol for a mixed-methods process evaluation of a randomised controlled trial.
Aitken LM, Emerson LM, Kydonaki K, Blackwood B, Creagh-Brown B, Lone NI, McKenzie CA, Reade MC, Weir CJ, Wise MP, Walsh TS. Aitken LM, et al. Among authors: reade mc. BMJ Open. 2024 Apr 5;14(4):e081637. doi: 10.1136/bmjopen-2023-081637. BMJ Open. 2024. PMID: 38580355 Free PMC article.
Does dexmedetomidine given as a premedication or intraoperatively reduce post-hospitalisation behaviour change in children? A study protocol for a randomised controlled trial in a tertiary paediatric hospital.
Lee-Archer P, McBride C, Paterson R, Reade M, Regli-von Ungern-Sternberg B, Long D. Lee-Archer P, et al. Among authors: reade m. BMJ Open. 2018 Apr 17;8(4):e019915. doi: 10.1136/bmjopen-2017-019915. BMJ Open. 2018. PMID: 29666130 Free PMC article.
Fresh Red Cells for Transfusion in Critically Ill Adults: An Economic Evaluation of the Standard Issue Transfusion Versus Fresher Red-Cell Use in Intensive Care (TRANSFUSE) Clinical Trial.
Irving A, Higgins A, Ady B, Bellomo R, Cooper DJ, French C, Gantner D, Harris A, Irving DO, Murray L, Nichol A, Petrie D, McQuilten ZK; Standard Issue Transfusion versus Fresher Red-Cell Use in Intensive Care (TRANSFUSE) Investigators and Australian and New Zealand Intensive Care Society Clinical Trials Group. Irving A, et al. Crit Care Med. 2019 Jul;47(7):e572-e579. doi: 10.1097/CCM.0000000000003781. Crit Care Med. 2019. PMID: 31008734
Protocol for a multicentre prehospital randomised controlled trial investigating tranexamic acid in severe trauma: the PATCH-Trauma trial.
Mitra B, Bernard S, Gantner D, Burns B, Reade MC, Murray L, Trapani T, Pitt V, McArthur C, Forbes A, Maegele M, Gruen RL; PATCH-Trauma study investigators; PATCH-Trauma Study investigators. Mitra B, et al. Among authors: reade mc. BMJ Open. 2021 Mar 15;11(3):e046522. doi: 10.1136/bmjopen-2020-046522. BMJ Open. 2021. PMID: 33722875 Free PMC article.
213 results