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300 results

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Page 1
Prevention of infections and fever to improve outcome in older patients with acute stroke (PRECIOUS): a randomised, open, phase III, multifactorial, clinical trial with blinded outcome assessment.
de Jonge JC, Sluis WM, Reinink H, Bath PM, Woodhouse LJ, Zweedijk B, van de Beek D, Aamodt AH, Alpers I, Ciccone A, Csiba L, Demotes J, Kõrv J, Kurkowska-Jastrzebska I, Dawson J, Macleod MR, Ntaios G, Poli S, Milionis H, Ricci S, Cenciarelli S, Candelaresi P, de Bruijn SF, Pathansali R, Krishnan K, Clarke B, Thomalla G, van der Worp HB; PRECIOUS investigators. de Jonge JC, et al. Among authors: ciccone a. Lancet Reg Health Eur. 2023 Dec 1;36:100782. doi: 10.1016/j.lanepe.2023.100782. eCollection 2024 Jan. Lancet Reg Health Eur. 2023. PMID: 38074444 Free PMC article.
Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial.
Sprigg N, Flaherty K, Appleton JP, Al-Shahi Salman R, Bereczki D, Beridze M, Christensen H, Ciccone A, Collins R, Czlonkowska A, Dineen RA, Duley L, Egea-Guerrero JJ, England TJ, Krishnan K, Laska AC, Law ZK, Ozturk S, Pocock SJ, Roberts I, Robinson TG, Roffe C, Seiffge D, Scutt P, Thanabalan J, Werring D, Whynes D, Bath PM; TICH-2 Investigators. Sprigg N, et al. Among authors: ciccone a. Lancet. 2018 May 26;391(10135):2107-2115. doi: 10.1016/S0140-6736(18)31033-X. Epub 2018 May 16. Lancet. 2018. PMID: 29778325 Free PMC article. Clinical Trial.
PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke. Rationale and design of a randomised, open, phase III, clinical trial with blinded outcome assessment.
Reinink H, de Jonge JC, Bath PM, van de Beek D, Berge E, Borregaard S, Ciccone A, Csiba L, Demotes J, Dippel DW, Kõrv J, Kurkowska-Jastrzebska I, Lees KR, Macleod MR, Ntaios G, Randall G, Thomalla G, van der Worp HB. Reinink H, et al. Among authors: ciccone a. Eur Stroke J. 2018 Sep;3(3):291-298. doi: 10.1177/2396987318772687. Epub 2018 Apr 30. Eur Stroke J. 2018. PMID: 30246150 Free PMC article.
Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT.
Sprigg N, Flaherty K, Appleton JP, Al-Shahi Salman R, Bereczki D, Beridze M, Ciccone A, Collins R, Dineen RA, Duley L, Egea-Guerrero JJ, England TJ, Karlinski M, Krishnan K, Laska AC, Law ZK, Ovesen C, Ozturk S, Pocock SJ, Roberts I, Robinson TG, Roffe C, Peters N, Scutt P, Thanabalan J, Werring D, Whynes D, Woodhouse L, Bath PM. Sprigg N, et al. Among authors: ciccone a. Health Technol Assess. 2019 Jul;23(35):1-48. doi: 10.3310/hta23350. Health Technol Assess. 2019. PMID: 31322116 Free PMC article. Clinical Trial.
Noncontrast Computed Tomography Signs as Predictors of Hematoma Expansion, Clinical Outcome, and Response to Tranexamic Acid in Acute Intracerebral Hemorrhage.
Law ZK, Ali A, Krishnan K, Bischoff A, Appleton JP, Scutt P, Woodhouse L, Pszczolkowski S, Cala LA, Dineen RA, England TJ, Ozturk S, Roffe C, Bereczki D, Ciccone A, Christensen H, Ovesen C, Bath PM, Sprigg N; TICH-2 Investigators. Law ZK, et al. Among authors: ciccone a. Stroke. 2020 Jan;51(1):121-128. doi: 10.1161/STROKEAHA.119.026128. Epub 2019 Nov 18. Stroke. 2020. PMID: 31735141 Free PMC article.
Predictors and Outcomes of Neurological Deterioration in Intracerebral Hemorrhage: Results from the TICH-2 Randomized Controlled Trial.
Law ZK, Dineen R, England TJ, Cala L, Mistri AK, Appleton JP, Ozturk S, Bereczki D, Ciccone A, Bath PM, Sprigg N; TICH-2 investigators. Law ZK, et al. Among authors: ciccone a. Transl Stroke Res. 2021 Apr;12(2):275-283. doi: 10.1007/s12975-020-00845-6. Epub 2020 Sep 9. Transl Stroke Res. 2021. PMID: 32902808 Free PMC article. Clinical Trial.
Regulatory delays in a multinational clinical stroke trial.
de Jonge JC, Reinink H, Colam B, Alpers I, Ciccone A, Csiba L, Kõrv J, Kurkowska-Jastrzebska I, Macleod MR, Ntaios G, Thomalla G, Bath PM, van der Worp HB. de Jonge JC, et al. Among authors: ciccone a. Eur Stroke J. 2021 Jun;6(2):120-127. doi: 10.1177/23969873211004845. Epub 2021 Mar 30. Eur Stroke J. 2021. PMID: 34414286 Free PMC article.
Brief Consent Methods Enable Rapid Enrollment in Acute Stroke Trial: Results From the TICH-2 Randomized Controlled Trial.
Law ZK, Appleton JP, Scutt P, Roberts I, Al-Shahi Salman R, England TJ, Werring DJ, Robinson T, Krishnan K, Dineen RA, Laska AC, Lyrer PA, Egea-Guerrero JJ, Karlinski M, Christensen H, Roffe C, Bereczki D, Ozturk S, Thanabalan J, Collins R, Beridze M, Ciccone A, Duley L, Shone A, Bath PM, Sprigg N; TICH-2 Investigators. Law ZK, et al. Among authors: ciccone a. Stroke. 2022 Apr;53(4):1141-1148. doi: 10.1161/STROKEAHA.121.035191. Epub 2021 Dec 1. Stroke. 2022. PMID: 34847710 Free PMC article. Clinical Trial.
The Effect of Tranexamic Acid on Neurosurgical Intervention in Spontaneous Intracerebral Hematoma: Data From 121 Surgically Treated Participants From the Tranexamic Acid in IntraCerebral Hemorrhage-2 Randomized Controlled Trial.
Hollingworth M, Woodhouse LJ, Law ZK, Ali A, Krishnan K, Dineen RA, Christensen H, England TJ, Roffe C, Werring D, Peters N, Ciccone A, Robinson T, Członkowska A, Bereczki D, Egea-Guerrero JJ, Ozturk S, Bath PM, Sprigg N; TICH-2 Investigators. Hollingworth M, et al. Among authors: ciccone a. Neurosurgery. 2024 May 24. doi: 10.1227/neu.0000000000002961. Online ahead of print. Neurosurgery. 2024. PMID: 38785451
300 results