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Page 1
Common and distinct metabolomic markers related to immune aging in Western European and East African populations.
Bulut O, Temba GS, Koeken VACM, Moorlag SJCFM, de Bree LCJ, Mourits VP, Kullaya VI, Jaeger M, Qi C, Riksen NP, Domínguez-Andrés J, Xu CJ, Joosten LAB, Li Y, de Mast Q, Netea MG. Bulut O, et al. Among authors: de bree lcj. Mech Ageing Dev. 2024 Apr;218:111916. doi: 10.1016/j.mad.2024.111916. Epub 2024 Feb 14. Mech Ageing Dev. 2024. PMID: 38364983 Free article.
Multi-omics analysis of innate and adaptive responses to BCG vaccination reveals epigenetic cell states that predict trained immunity.
Moorlag SJCFM, Folkman L, Ter Horst R, Krausgruber T, Barreca D, Schuster LC, Fife V, Matzaraki V, Li W, Reichl S, Mourits VP, Koeken VACM, de Bree LCJ, Dijkstra H, Lemmers H, van Cranenbroek B, van Rijssen E, Koenen HJPM, Joosten I, Xu CJ, Li Y, Joosten LAB, van Crevel R, Netea MG, Bock C. Moorlag SJCFM, et al. Among authors: de bree lcj. Immunity. 2024 Jan 9;57(1):171-187.e14. doi: 10.1016/j.immuni.2023.12.005. Immunity. 2024. PMID: 38198850 Free article.
BCG vaccination induces innate immune memory in γδ T cells in humans.
Suen TK, Moorlag SJCFM, Li W, de Bree LCJ, Koeken VACM, Mourits VP, Dijkstra H, Lemmers H, Bhat J, Xu CJ, Joosten LAB, Schultze JL, Li Y, Placek K, Netea MG. Suen TK, et al. Among authors: de bree lcj. J Leukoc Biol. 2024 Jan 5;115(1):149-163. doi: 10.1093/jleuko/qiad103. J Leukoc Biol. 2024. PMID: 37672677
A single-cell view on host immune transcriptional response to in vivo BCG-induced trained immunity.
Li W, Moorlag SJCFM, Koeken VACM, Röring RJ, de Bree LCJ, Mourits VP, Gupta MK, Zhang B, Fu J, Zhang Z, Grondman I, van Meijgaarden KE, Zhou L, Alaswad A, Joosten LAB, van Crevel R, Xu CJ, Netea MG, Li Y. Li W, et al. Among authors: de bree lcj. Cell Rep. 2023 May 30;42(5):112487. doi: 10.1016/j.celrep.2023.112487. Epub 2023 May 7. Cell Rep. 2023. PMID: 37155329 Free PMC article.
The impact of BCG dose and revaccination on trained immunity.
Debisarun PA, Kilic G, de Bree LCJ, Pennings LJ, van Ingen J, Benn CS, Aaby P, Dijkstra H, Lemmers H, Domínguez-Andrés J, van Crevel R, Netea MG. Debisarun PA, et al. Among authors: de bree lcj. Clin Immunol. 2023 Jan;246:109208. doi: 10.1016/j.clim.2022.109208. Epub 2022 Dec 21. Clin Immunol. 2023. PMID: 36565972 Free article. Clinical Trial.
Plasma metabolome predicts trained immunity responses after antituberculosis BCG vaccination.
Koeken VACM, Qi C, Mourits VP, de Bree LCJ, Moorlag SJCFM, Sonawane V, Lemmers H, Dijkstra H, Joosten LAB, van Laarhoven A, Xu CJ, van Crevel R, Netea MG, Li Y. Koeken VACM, et al. Among authors: de bree lcj. PLoS Biol. 2022 Sep 12;20(9):e3001765. doi: 10.1371/journal.pbio.3001765. eCollection 2022 Sep. PLoS Biol. 2022. PMID: 36094960 Free PMC article.
The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses.
Kuijpers Y, Chu X, Jaeger M, Moorlag SJCFM, Koeken VACM, Zhang B, de Nooijer A, Grondman I, Gupta MK, Janssen N, Mourits VP, de Bree LCJ, de Mast Q, van de Veerdonk FL, Joosten LAB, Li Y, Netea MG, Xu CJ. Kuijpers Y, et al. Among authors: de bree lcj. Front Immunol. 2022 May 12;13:859387. doi: 10.3389/fimmu.2022.859387. eCollection 2022. Front Immunol. 2022. PMID: 35634344 Free PMC article.
BCG-induced trained immunity enhances acellular pertussis vaccination responses in an explorative randomized clinical trial.
Gillard J, Blok BA, Garza DR, Venkatasubramanian PB, Simonetti E, Eleveld MJ, Berbers GAM, van Gageldonk PGM, Joosten I, de Groot R, de Bree LCJ, van Crevel R, de Jonge MI, Huynen MA, Netea MG, Diavatopoulos DA. Gillard J, et al. Among authors: de bree lcj. NPJ Vaccines. 2022 Feb 17;7(1):21. doi: 10.1038/s41541-022-00438-4. NPJ Vaccines. 2022. PMID: 35177621 Free PMC article.
An integrative genomics approach identifies KDM4 as a modulator of trained immunity.
Moorlag SJCFM, Matzaraki V, van Puffelen JH, van der Heijden C, Keating S, Groh L, Röring RJ, Bakker OB, Mourits VP, Koeken VACM, de Bree LCJ, Smeekens SP, Oosting M, Gamboa RA, Riksen NP, Xavier RJ, Wijmenga C, Kumar V, van Crevel R, Novakovic B, Joosten LAB, Li Y, Netea MG. Moorlag SJCFM, et al. Among authors: de bree lcj. Eur J Immunol. 2022 Mar;52(3):431-446. doi: 10.1002/eji.202149577. Epub 2021 Dec 10. Eur J Immunol. 2022. PMID: 34821391 Free PMC article.
40 results