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Page 1
TREM2 deficiency reprograms intestinal macrophages and microbiota to enhance anti-PD-1 tumor immunotherapy.
Di Luccia B, Molgora M, Khantakova D, Jaeger N, Chang HW, Czepielewski RS, Helmink BA, Onufer EJ, Fachi JL, Bhattarai B, Trsan T, Rodrigues PF, Hou J, Bando JK, da Silva CS, Cella M, Gilfillan S, Schreiber RD, Gordon JI, Colonna M. Di Luccia B, et al. Among authors: onufer ej. Sci Immunol. 2024 May 17;9(95):eadi5374. doi: 10.1126/sciimmunol.adi5374. Epub 2024 May 17. Sci Immunol. 2024. PMID: 38758808
Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis.
Canales-Herrerias P, Uzzan M, Seki A, Czepielewski RS, Verstockt B, Livanos AE, Raso F, Dunn A, Dai D, Wang A, Al-Taie Z, Martin J, Laurent T, Ko HM, Tokuyama M, Tankelevich M, Meringer H, Cossarini F, Jha D, Krek A, Paulsen JD, Taylor MD, Nakadar MZ, Wong J, Erlich EC, Mintz RL, Onufer EJ, Helmink BA, Sharma K, Rosenstein A, Ganjian D, Chung G, Dawson T, Juarez J, Yajnik V, Cerutti A, Faith JJ, Suarez-Farinas M, Argmann C, Petralia F, Randolph GJ, Polydorides AD, Reboldi A, Colombel JF, Mehandru S. Canales-Herrerias P, et al. Among authors: onufer ej. Sci Immunol. 2024 Apr 19;9(94):eadg7549. doi: 10.1126/sciimmunol.adg7549. Epub 2024 Apr 19. Sci Immunol. 2024. PMID: 38640252
Human serous cavity macrophages and dendritic cells possess counterparts in the mouse with a distinct distribution between species.
Han J, Gallerand A, Erlich EC, Helmink BA, Mair I, Li X, Eckhouse SR, Dimou FM, Shakhsheer BA, Phelps HM, Chan MM, Mintz RL, Lee DD, Schilling JD, Finlay CM, Allen JE, Jakubzick CV, Else KJ, Onufer EJ, Zhang N, Randolph GJ. Han J, et al. Among authors: onufer ej. Nat Immunol. 2024 Jan;25(1):155-165. doi: 10.1038/s41590-023-01688-7. Epub 2023 Dec 15. Nat Immunol. 2024. PMID: 38102487
Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis.
Canales-Herrerias P, Uzzan M, Seki A, Czepielewski RS, Verstockt B, Livanos A, Raso F, Dunn A, Dai D, Wang A, Al-Taie Z, Martin J, Ko HM, Tokuyama M, Tankelevich M, Meringer H, Cossarini F, Jha D, Krek A, Paulsen JD, Nakadar MZ, Wong J, Erlich EC, Onufer EJ, Helmink BA, Sharma K, Rosenstein A, Chung G, Dawson T, Juarez J, Yajnik V, Cerutti A, Faith J, Suarez-Farinas M, Argmann C, Petralia F, Randolph GJ, Polydorides AD, Reboldi A, Colombel JF, Mehandru S. Canales-Herrerias P, et al. Among authors: onufer ej. bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.524731. doi: 10.1101/2023.01.19.524731. bioRxiv. 2023. PMID: 36711839 Free PMC article. Updated. Preprint.
Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor.
Czepielewski RS, Erlich EC, Onufer EJ, Young S, Saunders BT, Han YH, Wohltmann M, Wang PL, Kim KW, Kumar S, Hsieh CS, Scallan JP, Yang Y, Zinselmeyer BH, Davis MJ, Randolph GJ. Czepielewski RS, et al. Among authors: onufer ej. Immunity. 2021 Dec 14;54(12):2795-2811.e9. doi: 10.1016/j.immuni.2021.10.003. Epub 2021 Nov 16. Immunity. 2021. PMID: 34788601 Free PMC article.
LYVE1+ macrophages of murine peritoneal mesothelium promote omentum-independent ovarian tumor growth.
Zhang N, Kim SH, Gainullina A, Erlich EC, Onufer EJ, Kim J, Czepielewski RS, Helmink BA, Dominguez JR, Saunders BT, Ding J, Williams JW, Jiang JX, Segal BH, Zinselmeyer BH, Randolph GJ, Kim KW. Zhang N, et al. Among authors: onufer ej. J Exp Med. 2021 Dec 6;218(12):e20210924. doi: 10.1084/jem.20210924. Epub 2021 Oct 29. J Exp Med. 2021. PMID: 34714329 Free PMC article.
SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling.
Gu W, Wang H, Huang X, Kraiczy J, Singh PNP, Ng C, Dagdeviren S, Houghton S, Pellon-Cardenas O, Lan Y, Nie Y, Zhang J, Banerjee KK, Onufer EJ, Warner BW, Spence J, Scherl E, Rafii S, Lee RT, Verzi MP, Redmond D, Longman R, Helin K, Shivdasani RA, Zhou Q. Gu W, et al. Among authors: onufer ej. Cell Stem Cell. 2022 Jan 6;29(1):101-115.e10. doi: 10.1016/j.stem.2021.09.004. Epub 2021 Sep 27. Cell Stem Cell. 2022. PMID: 34582804 Free PMC article.
25 results