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Oral Metformin Inhibits Choroidal Neovascularization by Modulating the Gut-Retina Axis.
Zhang JY, Xiao J, Xie B, Barba H, Boachie-Mensah M, Shah RN, Nadeem U, Spedale M, Dylla N, Lin H, Sidebottom AM, D'Souza M, Theriault B, Sulakhe D, Chang EB, Skondra D. Zhang JY, et al. Among authors: spedale m. Invest Ophthalmol Vis Sci. 2023 Dec 1;64(15):21. doi: 10.1167/iovs.64.15.21. Invest Ophthalmol Vis Sci. 2023. PMID: 38108689 Free PMC article.
The Host-specific Microbiota is Required for Diet-Specific Metabolic Homeostasis.
Fei N, Xie B, Long TJ, StGeorge M, Tan A, Manzoor S, Sidebottom AM, Spedale M, Theriault BR, Sulakhe D, Chang EB. Fei N, et al. Among authors: spedale m. bioRxiv [Preprint]. 2023 Nov 6:2023.11.05.565654. doi: 10.1101/2023.11.05.565654. bioRxiv. 2023. PMID: 37986759 Free PMC article. Preprint.
Absence of Gut Microbiota Is Associated with RPE/Choroid Transcriptomic Changes Related to Age-Related Macular Degeneration Pathobiology and Decreased Choroidal Neovascularization.
Zhang JY, Xie B, Barba H, Nadeem U, Movahedan A, Deng N, Spedale M, D'Souza M, Luo W, Leone V, Chang EB, Theriault B, Sulakhe D, Skondra D. Zhang JY, et al. Among authors: spedale m. Int J Mol Sci. 2022 Aug 26;23(17):9676. doi: 10.3390/ijms23179676. Int J Mol Sci. 2022. PMID: 36077073 Free PMC article.
Efficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico.
Dunkle LM, Kotloff KL, Gay CL, Áñez G, Adelglass JM, Barrat Hernández AQ, Harper WL, Duncanson DM, McArthur MA, Florescu DF, McClelland RS, Garcia-Fragoso V, Riesenberg RA, Musante DB, Fried DL, Safirstein BE, McKenzie M, Jeanfreau RJ, Kingsley JK, Henderson JA, Lane DC, Ruíz-Palacios GM, Corey L, Neuzil KM, Coombs RW, Greninger AL, Hutter J, Ake JA, Smith K, Woo W, Cho I, Glenn GM, Dubovsky F; 2019nCoV-301 Study Group. Dunkle LM, et al. N Engl J Med. 2022 Feb 10;386(6):531-543. doi: 10.1056/NEJMoa2116185. Epub 2021 Dec 15. N Engl J Med. 2022. PMID: 34910859 Free PMC article. Clinical Trial.