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Modifications to 1-(4-(2-Bis(4-fluorophenyl)methyl)sulfinyl)alkyl Alicyclic Amines That Improve Metabolic Stability and Retain an Atypical DAT Inhibitor Profile.
J Med Chem. 2024 Jan 11;67(1):709-727. doi: 10.1021/acs.jmedchem.3c02037. Epub 2023 Dec 20.
J Med Chem. 2024.
PMID: 38117239
Series of (([1,1'-Biphenyl]-2-yl)methyl)sulfinylalkyl Alicyclic Amines as Novel and High Affinity Atypical Dopamine Transporter Inhibitors with Reduced hERG Activity.
Ku TC, Cao J, Won SJ, Guo J, Camacho-Hernandez GA, Okorom AV, Salomon KW, Lee KH, Loland CJ, Duff HJ, Shi L, Newman AH.
Ku TC, et al. Among authors: okorom av.
ACS Pharmacol Transl Sci. 2024 Jan 5;7(2):515-532. doi: 10.1021/acsptsci.3c00322. eCollection 2024 Feb 9.
ACS Pharmacol Transl Sci. 2024.
PMID: 38357284
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Development of a Fluorescently Labeled Ligand for Rapid Detection of DAT in Human and Mouse Peripheral Blood Monocytes.
Camacho-Hernandez GA, Gopinath A, Okorom AV, Khoshbouei H, Newman AH.
Camacho-Hernandez GA, et al. Among authors: okorom av.
JACS Au. 2024 Jan 24;4(2):657-665. doi: 10.1021/jacsau.3c00719. eCollection 2024 Feb 26.
JACS Au. 2024.
PMID: 38425927
Free PMC article.
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