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Page 1
Preliminary Study on the Efficacy of a Recombinant, Subunit SARS-CoV-2 Animal Vaccine against Virulent SARS-CoV-2 Challenge in Cats.
Morozov I, Gaudreault NN, Trujillo JD, Indran SV, Cool K, Kwon T, Meekins DA, Balaraman V, Artiaga BL, Madden DW, McDowell C, Njaa B, Retallick J, Hainer N, Millership J, Wilson WC, Tkalcevic G, Vander Horst H, Burakova Y, King V, Hutchinson K, Hardham JM, Schwahn DJ, Kumar M, Richt JA. Morozov I, et al. Among authors: tkalcevic g. Vaccines (Basel). 2023 Dec 8;11(12):1831. doi: 10.3390/vaccines11121831. Vaccines (Basel). 2023. PMID: 38140233 Free PMC article.
Discovery of Selective Small Molecule Inhibitors of Monoacylglycerol Acyltransferase 3.
Huard K, Londregan AT, Tesz G, Bahnck KB, Magee TV, Hepworth D, Polivkova J, Coffey SB, Pabst BA, Gosset JR, Nigam A, Kou K, Sun H, Lee K, Herr M, Boehm M, Carpino PA, Goodwin B, Perreault C, Li Q, Jorgensen CC, Tkalcevic GT, Subashi TA, Ahn K. Huard K, et al. Among authors: tkalcevic gt. J Med Chem. 2015 Sep 24;58(18):7164-72. doi: 10.1021/acs.jmedchem.5b01008. Epub 2015 Sep 8. J Med Chem. 2015. PMID: 26258602
Discovery and synthesis of novel 4-aminopyrrolopyrimidine Tie-2 kinase inhibitors for the treatment of solid tumors.
Arcari JT, Beebe JS, Berliner MA, Bernardo V, Boehm M, Borzillo GV, Clark T, Cohen BD, Connell RD, Frost HN, Gordon DA, Hungerford WM, Kakar SM, Kanter A, Keene NF, Knauth EA, Lagreca SD, Lu Y, Martinez-Alsina L, Marx MA, Morris J, Patel NC, Savage D, Soderstrom CI, Thompson C, Tkalcevic G, Tom NJ, Vajdos FF, Valentine JJ, Vincent PW, Wessel MD, Chen JM. Arcari JT, et al. Among authors: tkalcevic g. Bioorg Med Chem Lett. 2013 May 15;23(10):3059-63. doi: 10.1016/j.bmcl.2013.03.012. Epub 2013 Mar 21. Bioorg Med Chem Lett. 2013. PMID: 23566514
Discovery of PF-04449913, a Potent and Orally Bioavailable Inhibitor of Smoothened.
Munchhof MJ, Li Q, Shavnya A, Borzillo GV, Boyden TL, Jones CS, LaGreca SD, Martinez-Alsina L, Patel N, Pelletier K, Reiter LA, Robbins MD, Tkalcevic GT. Munchhof MJ, et al. Among authors: tkalcevic gt. ACS Med Chem Lett. 2011 Dec 21;3(2):106-11. doi: 10.1021/ml2002423. eCollection 2012 Feb 9. ACS Med Chem Lett. 2011. PMID: 24900436 Free PMC article.
Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451.
Roberts WG, Whalen PM, Soderstrom E, Moraski G, Lyssikatos JP, Wang HF, Cooper B, Baker DA, Savage D, Dalvie D, Atherton JA, Ralston S, Szewc R, Kath JC, Lin J, Soderstrom C, Tkalcevic G, Cohen BD, Pollack V, Barth W, Hungerford W, Ung E. Roberts WG, et al. Among authors: tkalcevic g. Cancer Res. 2005 Feb 1;65(3):957-66. Cancer Res. 2005. PMID: 15705896
Discovery and preclinical pharmacology of a novel, potent, nonsteroidal estrogen receptor agonist/antagonist, CP-336156, a diaryltetrahydronaphthalene.
Rosati RL, Da Silva Jardine P, Cameron KO, Thompson DD, Ke HZ, Toler SM, Brown TA, Pan LC, Ebbinghaus CF, Reinhold AR, Elliott NC, Newhouse BN, Tjoa CM, Sweetnam PM, Cole MJ, Arriola MW, Gauthier JW, Crawford DT, Nickerson DF, Pirie CM, Qi H, Simmons HA, Tkalcevic GT. Rosati RL, et al. Among authors: tkalcevic gt. J Med Chem. 1998 Jul 30;41(16):2928-31. doi: 10.1021/jm980048b. J Med Chem. 1998. PMID: 9685230 No abstract available.
19 results