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Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of cell cycle.
Blood. 2024 May 28:blood.2023021426. doi: 10.1182/blood.2023021426. Online ahead of print.
Blood. 2024.
PMID: 38805639
Intrafemoral Injection of Human Hematopoietic Stem and Progenitor Cells into Immunocompromised Mice.
Calderbank EF, Magnani L, Laurenti E.
Calderbank EF, et al.
J Vis Exp. 2023 Dec 8;(202):10.3791/66315. doi: 10.3791/66315.
J Vis Exp. 2023.
PMID: 38145377
Free PMC article.
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Primitive haematopoiesis in the human placenta gives rise to macrophages with epigenetically silenced HLA-DR.
Thomas JR, Appios A, Calderbank EF, Yoshida N, Zhao X, Hamilton RS, Moffett A, Sharkey A, Laurenti E, Hanna CW, McGovern N.
Thomas JR, et al. Among authors: calderbank ef.
Nat Commun. 2023 Mar 30;14(1):1764. doi: 10.1038/s41467-023-37383-2.
Nat Commun. 2023.
PMID: 36997537
Free PMC article.
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Clonal dynamics of haematopoiesis across the human lifespan.
Mitchell E, Spencer Chapman M, Williams N, Dawson KJ, Mende N, Calderbank EF, Jung H, Mitchell T, Coorens THH, Spencer DH, Machado H, Lee-Six H, Davies M, Hayler D, Fabre MA, Mahbubani K, Abascal F, Cagan A, Vassiliou GS, Baxter J, Martincorena I, Stratton MR, Kent DG, Chatterjee K, Parsy KS, Green AR, Nangalia J, Laurenti E, Campbell PJ.
Mitchell E, et al. Among authors: calderbank ef.
Nature. 2022 Jun;606(7913):343-350. doi: 10.1038/s41586-022-04786-y. Epub 2022 Jun 1.
Nature. 2022.
PMID: 35650442
Free PMC article.
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Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans.
Mende N, Bastos HP, Santoro A, Mahbubani KT, Ciaurro V, Calderbank EF, Quiroga Londoño M, Sham K, Mantica G, Morishima T, Mitchell E, Lidonnici MR, Meier-Abt F, Hayler D, Jardine L, Curd A, Haniffa M, Ferrari G, Takizawa H, Wilson NK, Göttgens B, Saeb-Parsy K, Frontini M, Laurenti E.
Mende N, et al. Among authors: calderbank ef.
Blood. 2022 Jun 9;139(23):3387-3401. doi: 10.1182/blood.2021013450.
Blood. 2022.
PMID: 35073399
Free PMC article.
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Decoding human fetal liver haematopoiesis.
Popescu DM, Botting RA, Stephenson E, Green K, Webb S, Jardine L, Calderbank EF, Polanski K, Goh I, Efremova M, Acres M, Maunder D, Vegh P, Gitton Y, Park JE, Vento-Tormo R, Miao Z, Dixon D, Rowell R, McDonald D, Fletcher J, Poyner E, Reynolds G, Mather M, Moldovan C, Mamanova L, Greig F, Young MD, Meyer KB, Lisgo S, Bacardit J, Fuller A, Millar B, Innes B, Lindsay S, Stubbington MJT, Kowalczyk MS, Li B, Ashenberg O, Tabaka M, Dionne D, Tickle TL, Slyper M, Rozenblatt-Rosen O, Filby A, Carey P, Villani AC, Roy A, Regev A, Chédotal A, Roberts I, Göttgens B, Behjati S, Laurenti E, Teichmann SA, Haniffa M.
Popescu DM, et al. Among authors: calderbank ef.
Nature. 2019 Oct;574(7778):365-371. doi: 10.1038/s41586-019-1652-y. Epub 2019 Oct 9.
Nature. 2019.
PMID: 31597962
Free PMC article.
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Myelo-lymphoid lineage restriction occurs in the human haematopoietic stem cell compartment before lymphoid-primed multipotent progenitors.
Belluschi S, Calderbank EF, Ciaurro V, Pijuan-Sala B, Santoro A, Mende N, Diamanti E, Sham KYC, Wang X, Lau WWY, Jawaid W, Göttgens B, Laurenti E.
Belluschi S, et al. Among authors: calderbank ef.
Nat Commun. 2018 Oct 5;9(1):4100. doi: 10.1038/s41467-018-06442-4.
Nat Commun. 2018.
PMID: 30291229
Free PMC article.
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