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A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis.
Adolph C, Cheung CY, McNeil MB, Jowsey WJ, Williams ZC, Hards K, Harold LK, Aboelela A, Bujaroski RS, Buckley BJ, Tyndall JDA, Li Z, Langer JD, Preiss L, Meier T, Steyn AJC, Rhee KY, Berney M, Kelso MJ, Cook GM. Adolph C, et al. Among authors: cook gm. Cell Chem Biol. 2024 Apr 18;31(4):683-698.e7. doi: 10.1016/j.chembiol.2023.12.002. Epub 2023 Dec 26. Cell Chem Biol. 2024. PMID: 38151019
A tridecameric c ring of the adenosine triphosphate (ATP) synthase from the thermoalkaliphilic Bacillus sp. strain TA2.A1 facilitates ATP synthesis at low electrochemical proton potential.
Meier T, Morgner N, Matthies D, Pogoryelov D, Keis S, Cook GM, Dimroth P, Brutschy B. Meier T, et al. Among authors: cook gm. Mol Microbiol. 2007 Sep;65(5):1181-92. doi: 10.1111/j.1365-2958.2007.05857.x. Epub 2007 Jul 21. Mol Microbiol. 2007. PMID: 17645441 Free article.
Physiology of mycobacteria.
Cook GM, Berney M, Gebhard S, Heinemann M, Cox RA, Danilchanka O, Niederweis M. Cook GM, et al. Adv Microb Physiol. 2009;55:81-182, 318-9. doi: 10.1016/S0065-2911(09)05502-7. Adv Microb Physiol. 2009. PMID: 19573696 Free PMC article. Review.
Draft genome sequence of the thermoalkaliphilic Caldalkalibacillus thermarum strain TA2.A1.
Kalamorz F, Keis S, McMillan DG, Olsson K, Stanton JA, Stockwell P, Black MA, Klingeman DM, Land ML, Han CS, Martin SL, Becher SA, Peddie CJ, Morgan HW, Matthies D, Preiss L, Meier T, Brown SD, Cook GM. Kalamorz F, et al. Among authors: cook gm. J Bacteriol. 2011 Aug;193(16):4290-1. doi: 10.1128/JB.05035-11. Epub 2011 Jun 17. J Bacteriol. 2011. PMID: 21685297 Free PMC article.
331 results