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Page 1
The pathophysiology of sepsis and precision-medicine-based immunotherapy.
Giamarellos-Bourboulis EJ, Aschenbrenner AC, Bauer M, Bock C, Calandra T, Gat-Viks I, Kyriazopoulou E, Lupse M, Monneret G, Pickkers P, Schultze JL, van der Poll T, van de Veerdonk FL, Vlaar APJ, Weis S, Wiersinga WJ, Netea MG. Giamarellos-Bourboulis EJ, et al. Among authors: pickkers p. Nat Immunol. 2024 Jan;25(1):19-28. doi: 10.1038/s41590-023-01660-5. Epub 2024 Jan 2. Nat Immunol. 2024. PMID: 38168953 Review.
Effect of Human Recombinant Alkaline Phosphatase on 7-Day Creatinine Clearance in Patients With Sepsis-Associated Acute Kidney Injury: A Randomized Clinical Trial.
Pickkers P, Mehta RL, Murray PT, Joannidis M, Molitoris BA, Kellum JA, Bachler M, Hoste EAJ, Hoiting O, Krell K, Ostermann M, Rozendaal W, Valkonen M, Brealey D, Beishuizen A, Meziani F, Murugan R, de Geus H, Payen D, van den Berg E, Arend J; STOP-AKI Investigators. Pickkers P, et al. JAMA. 2018 Nov 20;320(19):1998-2009. doi: 10.1001/jama.2018.14283. JAMA. 2018. PMID: 30357272 Free PMC article. Clinical Trial.
Towards personalized medicine: a scoping review of immunotherapy in sepsis.
Slim MA, van Mourik N, Bakkerus L, Fuller K, Acharya L, Giannidis T, Dionne JC, Oczkowski SJW, Netea MG, Pickkers P, Giamarellos-Bourboulis EJ, Müller MCA, van der Poll T, Wiersinga WJ; ImmunoSep Consortium; Vlaar APJ, van Vught LA. Slim MA, et al. Among authors: pickkers p. Crit Care. 2024 May 28;28(1):183. doi: 10.1186/s13054-024-04964-6. Crit Care. 2024. PMID: 38807151 Free PMC article. Review.
Corrigendum to "Systemic inflammation relates to neuroaxonal damage associated with long-term cognitive dysfunction in COVID-19 patients" [Brain Behav. Immun. 117 (2024) 510-520].
Duindam HB, Mengel D, Kox M, Göpfert JC, Kessels RPC, Synofzik M, Pickkers P, Abdo WF. Duindam HB, et al. Among authors: pickkers p. Brain Behav Immun. 2024 May 9:S0889-1591(24)00368-4. doi: 10.1016/j.bbi.2024.04.020. Online ahead of print. Brain Behav Immun. 2024. PMID: 38729788 Free article. No abstract available.
Phosphodiesterase 3 inhibitors do not influence lactate kinetics and clinical outcomes in patients with septic shock: A multicentre cohort study.
Tai-Passmann S, Slegers CAD, Hemelaar P, Waalders N, Koopmans M, van den Bogaard B, van Lookeren Campagne M, Goedegebuur J, Kuindersma M, Schroten N, van der Elsen F, Grady BPX, van den Beuken WMF, Kiers D, Pickkers P, van den Oever HLA; Research Collaboration Critical Care Netherlands (RCCNet), Piladys (PDE3i and lactate dynamics in septic shock) working group. Tai-Passmann S, et al. Among authors: pickkers p. J Crit Care. 2024 May 7;83:154827. doi: 10.1016/j.jcrc.2024.154827. Online ahead of print. J Crit Care. 2024. PMID: 38718462
The effect of immunosuppressive therapies on the endothelial host response in critically ill COVID-19 patients.
Slim MA, Lim EHT, van Vught LA, Boer AMT, Rademaker E, Mulier JLGH, Engel JJ; Amsterdam UMC COVID-19 Biobank Study Group; Radboudumc Center for Infectious Diseases COVID-19 Study Group; Pickkers P, van de Veerdonk FL, Vlaar APJ, Derde LPG, Juffermans NP. Slim MA, et al. Among authors: pickkers p. Sci Rep. 2024 Apr 20;14(1):9113. doi: 10.1038/s41598-024-59385-w. Sci Rep. 2024. PMID: 38643179 Free PMC article.
Sepsis-associated acute kidney injury: recent advances in enrichment strategies, sub-phenotyping and clinical trials.
Legrand M, Bagshaw SM, Bhatraju PK, Bihorac A, Caniglia E, Khanna AK, Kellum JA, Koyner J, Harhay MO, Zampieri FG, Zarbock A, Chung K, Liu K, Mehta R, Pickkers P, Ryan A, Bernholz J, Dember L, Gallagher M, Rossignol P, Ostermann M. Legrand M, et al. Among authors: pickkers p. Crit Care. 2024 Mar 21;28(1):92. doi: 10.1186/s13054-024-04877-4. Crit Care. 2024. PMID: 38515121 Free PMC article. Review.
Correction: Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL).
Pickkers P, Angus DC, Bass K, Bellomo R, van den Berg E, Bernholz J, Bestle MH, Doi K, Doig CJ, Ferrer R, Francois B, Gammelager H, Pedersen UG, Hoste E, Iversen S, Joannidis M, Kellum JA, Liu K, Meersch M, Mehta R, Millington S, Murray PT, Nichol A, Ostermann M, Pettilä V, Solling C, Winkel M, Young PJ, Zarbock A; REVIVAL investigators. Pickkers P, et al. Intensive Care Med. 2024 Apr;50(4):614-615. doi: 10.1007/s00134-024-07357-z. Intensive Care Med. 2024. PMID: 38436728 Free PMC article. No abstract available.
573 results