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Page 1
Natural history of Ebola virus disease in rhesus monkeys shows viral variant emergence dynamics and tissue-specific host responses.
Normandin E, Triana S, Raju SS, Lan TCT, Lagerborg K, Rudy M, Adams GC, DeRuff KC, Logue J, Liu D, Strebinger D, Rao A, Messer KS, Sacks M, Adams RD, Janosko K, Kotliar D, Shah R, Crozier I, Rinn JL, Melé M, Honko AN, Zhang F, Babadi M, Luban J, Bennett RS, Shalek AK, Barkas N, Lin AE, Hensley LE, Sabeti PC, Siddle KJ. Normandin E, et al. Among authors: lagerborg k. Cell Genom. 2023 Nov 21;3(12):100440. doi: 10.1016/j.xgen.2023.100440. eCollection 2023 Dec 13. Cell Genom. 2023. PMID: 38169842 Free PMC article.
Quantitative Comparison of Statistical Methods for Analyzing Human Metabolomics Data.
Henglin M, Claggett BL, Antonelli J, Alotaibi M, Magalang GA, Watrous JD, Lagerborg KA, Ovsak G, Musso G, Demler OV, Vasan RS, Larson MG, Jain M, Cheng S. Henglin M, et al. Among authors: lagerborg ka. Metabolites. 2022 Jun 4;12(6):519. doi: 10.3390/metabo12060519. Metabolites. 2022. PMID: 35736452 Free PMC article.
A plasma metabolite score of three eicosanoids predicts incident type 2 diabetes: a prospective study in three independent cohorts.
Tuomisto K, Palmu J, Long T, Watrous JD, Mercader K, Lagerborg KA, Andres A, Salmi M, Jalkanen S, Vasan RS, Inouye M, Havulinna AS, Tuomilehto J, Jousilahti P, Niiranen TJ, Cheng S, Jain M, Salomaa V. Tuomisto K, et al. Among authors: lagerborg ka. BMJ Open Diabetes Res Care. 2022 Mar;10(2):e002519. doi: 10.1136/bmjdrc-2021-002519. BMJ Open Diabetes Res Care. 2022. PMID: 35361620 Free PMC article.
Synthetic DNA spike-ins (SDSIs) enable sample tracking and detection of inter-sample contamination in SARS-CoV-2 sequencing workflows.
Lagerborg KA, Normandin E, Bauer MR, Adams G, Figueroa K, Loreth C, Gladden-Young A, Shaw BM, Pearlman LR, Berenzy D, Dewey HB, Kales S, Dobbins ST, Shenoy ES, Hooper D, Pierce VM, Zachary KC, Park DJ, MacInnis BL, Tewhey R, Lemieux JE, Sabeti PC, Reilly SK, Siddle KJ. Lagerborg KA, et al. Nat Microbiol. 2022 Jan;7(1):108-119. doi: 10.1038/s41564-021-01019-2. Epub 2021 Dec 14. Nat Microbiol. 2022. PMID: 34907347 Free PMC article.
Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species.
Tabebordbar M, Lagerborg KA, Stanton A, King EM, Ye S, Tellez L, Krunnfusz A, Tavakoli S, Widrick JJ, Messemer KA, Troiano EC, Moghadaszadeh B, Peacker BL, Leacock KA, Horwitz N, Beggs AH, Wagers AJ, Sabeti PC. Tabebordbar M, et al. Among authors: lagerborg ka. Cell. 2021 Sep 16;184(19):4919-4938.e22. doi: 10.1016/j.cell.2021.08.028. Epub 2021 Sep 9. Cell. 2021. PMID: 34506722 Free PMC article.
The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer.
Golden E, Rashwan R, Woodward EA, Sgro A, Wang E, Sorolla A, Waryah C, Tie WJ, Cuyàs E, Ratajska M, Kardaś I, Kozlowski P, Johnstone EKM, See HB, Duffy C, Parry J, Lagerborg KA, Czapiewski P, Menendez JA, Gorczyński A, Wasag B, Pfleger KDG, Curtis C, Lee BK, Kim J, Cursons J, Pavlos NJ, Biernat W, Jain M, Woo AJ, Redfern A, Blancafort P. Golden E, et al. Among authors: lagerborg ka. Nat Commun. 2021 Mar 26;12(1):1920. doi: 10.1038/s41467-021-22101-7. Nat Commun. 2021. PMID: 33772001 Free PMC article.
DNA spike-ins enable confident interpretation of SARS-CoV-2 genomic data from amplicon-based sequencing.
Lagerborg KA, Normandin E, Bauer MR, Adams G, Figueroa K, Loreth C, Gladden-Young A, Shaw B, Pearlman L, Shenoy ES, Hooper D, Pierce VM, Zachary KC, Park DJ, MacInnis BL, Lemieux JE, Sabeti PC, Reilly SK, Siddle KJ. Lagerborg KA, et al. bioRxiv [Preprint]. 2021 Mar 16:2021.03.16.435654. doi: 10.1101/2021.03.16.435654. bioRxiv. 2021. PMID: 33758855 Free PMC article. Preprint.
Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events.
Lemieux JE, Siddle KJ, Shaw BM, Loreth C, Schaffner SF, Gladden-Young A, Adams G, Fink T, Tomkins-Tinch CH, Krasilnikova LA, DeRuff KC, Rudy M, Bauer MR, Lagerborg KA, Normandin E, Chapman SB, Reilly SK, Anahtar MN, Lin AE, Carter A, Myhrvold C, Kemball ME, Chaluvadi S, Cusick C, Flowers K, Neumann A, Cerrato F, Farhat M, Slater D, Harris JB, Branda JA, Hooper D, Gaeta JM, Baggett TP, O'Connell J, Gnirke A, Lieberman TD, Philippakis A, Burns M, Brown CM, Luban J, Ryan ET, Turbett SE, LaRocque RC, Hanage WP, Gallagher GR, Madoff LC, Smole S, Pierce VM, Rosenberg E, Sabeti PC, Park DJ, MacInnis BL. Lemieux JE, et al. Among authors: lagerborg ka. Science. 2021 Feb 5;371(6529):eabe3261. doi: 10.1126/science.abe3261. Epub 2020 Dec 10. Science. 2021. PMID: 33303686 Free PMC article.
Mapping choline metabolites in normal and transformed cells.
Roci I, Watrous JD, Lagerborg KA, Jain M, Nilsson R. Roci I, et al. Among authors: lagerborg ka. Metabolomics. 2020 Nov 29;16(12):125. doi: 10.1007/s11306-020-01749-0. Metabolomics. 2020. PMID: 33249526 Free PMC article.
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