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Immunoglobulin replacement products protect against SARS-CoV-2 infection in vivo despite poor neutralizing activity.
Zimmerman O, Altman Doss AM, Ying B, Liang CY, Mackin SR, Davis-Adams HG, Adams LJ, VanBlargan LA, Chen RE, Scheaffer SM, Desai P, Raju S, Mantia TL, O'Shaughnessy CC, Monroy JM, Wedner HJ, Rigell CJ, Kau AL, Dy TB, Ren Z, Turner JS, O'Halloran JA, Presti RM, Kendall PL, Fremont DH, Ellebedy AH, Diamond MS. Zimmerman O, et al. Among authors: adams lj. JCI Insight. 2024 Feb 8;9(3):e176359. doi: 10.1172/jci.insight.176359. JCI Insight. 2024. PMID: 38175703 Free PMC article.
mRNA vaccine boosting enhances antibody responses against SARS-CoV-2 Omicron variant in individuals with antibody deficiency syndromes.
Zimmerman O, Altman Doss AM, Kaplonek P, Liang CY, VanBlargan LA, Chen RE, Monroy JM, Wedner HJ, Kulczycki A Jr, Mantia TL, O'Shaughnessy CC, Davis-Adams HG, Bertera HL, Adams LJ, Raju S, Zhao FR, Rigell CJ, Dy TB, Kau AL, Ren Z, Turner JS, O'Halloran JA, Presti RM, Fremont DH, Kendall PL, Ellebedy AH, Alter G, Diamond MS. Zimmerman O, et al. Among authors: adams lj. Cell Rep Med. 2022 Jun 21;3(6):100653. doi: 10.1016/j.xcrm.2022.100653. Epub 2022 Jun 9. Cell Rep Med. 2022. PMID: 35688161 Free PMC article.
An intranasal vaccine durably protects against SARS-CoV-2 variants in mice.
Hassan AO, Shrihari S, Gorman MJ, Ying B, Yuan D, Raju S, Chen RE, Dmitriev IP, Kashentseva E, Adams LJ, Mann C, Davis-Gardner ME, Suthar MS, Shi PY, Saphire EO, Fremont DH, Curiel DT, Alter G, Diamond MS. Hassan AO, et al. Among authors: adams lj. Cell Rep. 2021 Jul 27;36(4):109452. doi: 10.1016/j.celrep.2021.109452. Epub 2021 Jul 10. Cell Rep. 2021. PMID: 34289385 Free PMC article.
A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope.
VanBlargan LA, Adams LJ, Liu Z, Chen RE, Gilchuk P, Raju S, Smith BK, Zhao H, Case JB, Winkler ES, Whitener BM, Droit L, Aziati ID, Bricker TL, Joshi A, Shi PY, Creanga A, Pegu A, Handley SA, Wang D, Boon ACM, Crowe JE Jr, Whelan SPJ, Fremont DH, Diamond MS. VanBlargan LA, et al. Among authors: adams lj. Immunity. 2021 Oct 12;54(10):2399-2416.e6. doi: 10.1016/j.immuni.2021.08.016. Epub 2021 Aug 19. Immunity. 2021. PMID: 34481543 Free PMC article.
Antibody-mediated immunity to SARS-CoV-2 spike.
Errico JM, Adams LJ, Fremont DH. Errico JM, et al. Among authors: adams lj. Adv Immunol. 2022;154:1-69. doi: 10.1016/bs.ai.2022.07.001. Epub 2022 Aug 22. Adv Immunol. 2022. PMID: 36038194 Free PMC article. Review.
SARS-CoV-2 booster vaccination rescues attenuated IgG1 memory B cell response in primary antibody deficiency patients.
Lin FJ, Doss AMA, Davis-Adams HG, Adams LJ, Hanson CH, VanBlargan LA, Liang CY, Chen RE, Monroy JM, Wedner HJ, Kulczycki A, Mantia TL, O'Shaughnessy CC, Raju S, Zhao FR, Rizzi E, Rigell CJ, Dy TB, Kau AL, Ren Z, Turner JS, O'Halloran JA, Presti RM, Fremont DH, Kendall PL, Ellebedy AH, Mudd PA, Diamond MS, Zimmerman O, Laidlaw BJ. Lin FJ, et al. Among authors: adams lj. Front Immunol. 2022 Dec 22;13:1033770. doi: 10.3389/fimmu.2022.1033770. eCollection 2022. Front Immunol. 2022. PMID: 36618402 Free PMC article.
A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2.
Hassan AO, Kafai NM, Dmitriev IP, Fox JM, Smith BK, Harvey IB, Chen RE, Winkler ES, Wessel AW, Case JB, Kashentseva E, McCune BT, Bailey AL, Zhao H, VanBlargan LA, Dai YN, Ma M, Adams LJ, Shrihari S, Danis JE, Gralinski LE, Hou YJ, Schäfer A, Kim AS, Keeler SP, Weiskopf D, Baric RS, Holtzman MJ, Fremont DH, Curiel DT, Diamond MS. Hassan AO, et al. Among authors: adams lj. Cell. 2020 Oct 1;183(1):169-184.e13. doi: 10.1016/j.cell.2020.08.026. Epub 2020 Aug 19. Cell. 2020. PMID: 32931734 Free PMC article.
89 results