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De novo design of diverse small molecule binders and sensors using Shape Complementary Pseudocycles.
An L, Said M, Tran L, Majumder S, Goreshnik I, Lee GR, Juergens D, Dauparas J, Anishchenko I, Coventry B, Bera AK, Kang A, Levine PM, Alvarez V, Pillai A, Norn C, Feldman D, Zorine D, Hicks DR, Li X, Sanchez MG, Vafeados DK, Salveson PJ, Vorobieva AA, Baker D. An L, et al. Among authors: salveson pj. bioRxiv [Preprint]. 2023 Dec 21:2023.12.20.572602. doi: 10.1101/2023.12.20.572602. bioRxiv. 2023. PMID: 38187589 Free PMC article. Preprint.
Generation of Potent and Stable GLP-1 Analogues Via "Serine Ligation".
Levine PM, Craven TW, Li X, Balana AT, Bird GH, Godes M, Salveson PJ, Erickson PW, Lamb M, Ahlrichs M, Murphy M, Ogohara C, Said MY, Walensky LD, Pratt MR, Baker D. Levine PM, et al. Among authors: salveson pj. ACS Chem Biol. 2022 Apr 15;17(4):804-809. doi: 10.1021/acschembio.2c00075. Epub 2022 Mar 23. ACS Chem Biol. 2022. PMID: 35319882 Free PMC article.
An Improved Turn Structure for Inducing β-Hairpin Formation in Peptides.
Li X, Sabol AL, Wierzbicki M, Salveson PJ, Nowick JS. Li X, et al. Among authors: salveson pj. Angew Chem Int Ed Engl. 2021 Oct 11;60(42):22776-22782. doi: 10.1002/anie.202105559. Epub 2021 Sep 12. Angew Chem Int Ed Engl. 2021. PMID: 34258835 Free PMC article.
Repurposing Triphenylmethane Dyes to Bind to Trimers Derived from Aβ.
Salveson PJ, Haerianardakani S, Thuy-Boun A, Yoo S, Kreutzer AG, Demeler B, Nowick JS. Salveson PJ, et al. J Am Chem Soc. 2018 Sep 19;140(37):11745-11754. doi: 10.1021/jacs.8b06568. Epub 2018 Sep 6. J Am Chem Soc. 2018. PMID: 30125493 Free PMC article.
A Hexamer of a Peptide Derived from Aβ16-36.
Kreutzer AG, Spencer RK, McKnelly KJ, Yoo S, Hamza IL, Salveson PJ, Nowick JS. Kreutzer AG, et al. Among authors: salveson pj. Biochemistry. 2017 Nov 14;56(45):6061-6071. doi: 10.1021/acs.biochem.7b00831. Epub 2017 Oct 27. Biochemistry. 2017. PMID: 29028351 Free PMC article.
13 results